Results 81 to 90 of about 3,437 (186)
Organ Transplantation: Current Status, Challenges, and Future Prospects
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley +1 more source
The molecular basis of allorecognition in ascidians
AbstractThe process of allorecognition consists of an ability to discriminate self from non‐self. This discrimination is used either to identify non‐self cells and reject them (“non‐self histocompatibility”) or to identify self cells and reject them (as in the avoidance of self‐fertilization by hermaphrodites (“self incompatibility”).
openaire +2 more sources
Alloantibody Generation and Effector Function Following Sensitization To Human Leukocyte Antigen
Allorecognition is the activation of the adaptive immune system to foreign Human Leukocyte Antigen (HLA) resulting in the generation of alloantibodies.
Michelle J Hickey +2 more
doaj +1 more source
Abstract Introduction Restoring coral reefs through larval enhancement has the potential to scale interventions beyond experimental plots of tens of m2. However, the effectiveness of releasing larvae without confinement (“free release”) remains untested.
Marine Gouezo +9 more
wiley +1 more source
ABSTRACT Microvascular inflammation (MVI) in kidney allografts in the absence of detectable donor‐specific anti‐HLA antibodies (DSA) is increasingly recognised as a cause of premature graft failure following kidney transplantation. Potential mechanisms include NK cell alloreactivity mediated by recognition of mismatched HLA class I molecules (missing ...
Laura Knödl +8 more
wiley +1 more source
Molecular basis of allorecognition in the colonial cnidarian Hydractinia symbiolongicarpus [PDF]
Allorecognition is the ability to distinguish between self tissues and those of conspecifics. Among cnidarians, the molecular basis of allorecognition is best understood in the colonial hydroid, Hydractinia.
Huene, Aidan Lorraine
core
The effects of polymer-mediated immunocamouflage on allorecognition of blood cells
Allorecognition initiates the adverse events of red blood cell (RBC) alloimunization and tissue rejection. Current clinical approaches utilize tissue matching (HLA and blood typing) and immunosuppressive agents to attenuate allorecognition.
Price, Dana
core +1 more source
Background Genes involved in non-self recognition and host defence are typically capable of rapid diversification and exploit specialized genetic mechanism to that end.
Paoletti Mathieu +3 more
doaj +1 more source
Allorecognition mechanisms during ascidian fertilization
Ascidians (primitive chordates) are hermaphroditic animals, releasing sperm and eggs nearly simultaneously. But, many ascidians, including Ciona intestinalis and Halocynthia roretzi, show self-sterility or preference for cross-fertilization rather than self-fertilization.
Yoshito, Harada, Hitoshi, Sawada
openaire +3 more sources
Allorecognition of HLA-DP by CD4+T cells is affected by polymorphism in its alpha chain
Alloreactivity to HLA-DP molecules, class II heterodimers of an oligomorphic alpha and a polymorphic beta chain, is increasingly being studied due to its relevance in clinical transplantation.
Voorter, Christina E. M. +15 more
core +1 more source

