Results 81 to 90 of about 3,437 (186)

Organ Transplantation: Current Status, Challenges, and Future Prospects

open access: yesMedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

The molecular basis of allorecognition in ascidians

open access: yesBioEssays, 2008
AbstractThe process of allorecognition consists of an ability to discriminate self from non‐self. This discrimination is used either to identify non‐self cells and reject them (“non‐self histocompatibility”) or to identify self cells and reject them (as in the avoidance of self‐fertilization by hermaphrodites (“self incompatibility”).
openaire   +2 more sources

Alloantibody Generation and Effector Function Following Sensitization To Human Leukocyte Antigen

open access: yesFrontiers in Immunology, 2016
Allorecognition is the activation of the adaptive immune system to foreign Human Leukocyte Antigen (HLA) resulting in the generation of alloantibodies.
Michelle J Hickey   +2 more
doaj   +1 more source

Coral larval enhancement with and without nets yields similar recruitment during slack current releases

open access: yesRestoration Ecology, Volume 34, Issue 1, January 2026.
Abstract Introduction Restoring coral reefs through larval enhancement has the potential to scale interventions beyond experimental plots of tens of m2. However, the effectiveness of releasing larvae without confinement (“free release”) remains untested.
Marine Gouezo   +9 more
wiley   +1 more source

Acute Rejection With DSA‐Negative Severe Microvascular Inflammation in a Kidney Transplant Recipient With an Isolated DPB1*04‐Mismatch Successfully Stabilised With Daratumumab

open access: yesHLA, Volume 107, Issue 1, January 2026.
ABSTRACT Microvascular inflammation (MVI) in kidney allografts in the absence of detectable donor‐specific anti‐HLA antibodies (DSA) is increasingly recognised as a cause of premature graft failure following kidney transplantation. Potential mechanisms include NK cell alloreactivity mediated by recognition of mismatched HLA class I molecules (missing ...
Laura Knödl   +8 more
wiley   +1 more source

Molecular basis of allorecognition in the colonial cnidarian Hydractinia symbiolongicarpus [PDF]

open access: yes, 2022
Allorecognition is the ability to distinguish between self tissues and those of conspecifics. Among cnidarians, the molecular basis of allorecognition is best understood in the colonial hydroid, Hydractinia.
Huene, Aidan Lorraine
core  

The effects of polymer-mediated immunocamouflage on allorecognition of blood cells

open access: yes, 2015
Allorecognition initiates the adverse events of red blood cell (RBC) alloimunization and tissue rejection. Current clinical approaches utilize tissue matching (HLA and blood typing) and immunosuppressive agents to attenuate allorecognition.
Price, Dana
core   +1 more source

WD-repeat instability and diversification of the Podospora anserina hnwd non-self recognition gene family

open access: yesBMC Evolutionary Biology, 2010
Background Genes involved in non-self recognition and host defence are typically capable of rapid diversification and exploit specialized genetic mechanism to that end.
Paoletti Mathieu   +3 more
doaj   +1 more source

Allorecognition mechanisms during ascidian fertilization

open access: yesThe International Journal of Developmental Biology, 2008
Ascidians (primitive chordates) are hermaphroditic animals, releasing sperm and eggs nearly simultaneously. But, many ascidians, including Ciona intestinalis and Halocynthia roretzi, show self-sterility or preference for cross-fertilization rather than self-fertilization.
Yoshito, Harada, Hitoshi, Sawada
openaire   +3 more sources

Allorecognition of HLA-DP by CD4+T cells is affected by polymorphism in its alpha chain

open access: yes, 2014
Alloreactivity to HLA-DP molecules, class II heterodimers of an oligomorphic alpha and a polymorphic beta chain, is increasingly being studied due to its relevance in clinical transplantation.
Voorter, Christina E. M.   +15 more
core   +1 more source

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