Results 71 to 80 of about 3,437 (186)
Summary Background Tendinopathies in racehorses are challenging to treat, and restoring normal tendon composition remains elusive despite extensive research. Equine multipotent mesenchymal stromal cells (MSC) have shown promise for tendon repair, and various sources of MSC have been described.
A. Merchan Muñoz +7 more
wiley +1 more source
ABSTRACT Matching of HLA‐A, ‐B and ‐DRB1 is the gold standard in histocompatibility testing for kidney transplantation. A good HLA match reduces the risk of alloimmunisation, thereby decreasing the likelihood of graft failure and potentially enabling reduced immunosuppression therapy. However, the role of the non‐classical HLA and MIC genes is not well
Silja Tammi +6 more
wiley +1 more source
Genetic Diversity of Sexually Propagated Corals Is Maintained From the Aquarium to the Reef
ABSTRACT Amidst global reef declines, large‐scale coral aquaculture is being developed to support reef intervention. Genetic diversity underpins population resilience and therefore it is critical that aquaculture methods maintain diversity. However, it remains unclear how genetic diversity of coral progeny is shaped by (1) parental genetic composition,
Genevieve Dallmeyer‐Drennen +4 more
wiley +1 more source
Intercellular transfer of MHC molecules in T cell alloimmunity and allotransplantation
After transplantation of allogeneic tissues and organs, recognition by recipient T cells of donor MHC molecules initiates the pro-inflammatory adaptive immune response leading to allograft rejection.
Gilles Benichou, Hyshem H. Lancia
doaj +1 more source
Sponges, despite their simple body plan, discriminate between self and nonself with remarkable specificity. Sponge grafting experiments simulate the effects of natural self or nonself contact under laboratory conditions.
Laura F. Grice, Bernard M. Degnan
doaj +1 more source
Allorecognition is known to involve a large number of lymphocytes carrying diverse T-cell receptor repertoire. Thus, one way to understand allorecognition and rejection mechanisms is via high-throughput sequencing of T-cell receptors.
Aleksei Bulygin +5 more
core +1 more source
Lessons in modularity: the evolutionary ecology of colonial invertebrates
Benthic colonial invertebrates share with higher plants a modular construction and a sessile adult life. Both types of organism show parallel evolutionary responses to common selective forces, but in contrast to the long-established focus on plants ...
Roger N. Hughes
doaj +1 more source
Fifty Years of Natural Killer Cells: Milestones and Future Horizons
To mark 50 years of NK cell research, a 2025 Karolinska symposium traced discoveries from spontaneous cytotoxicity and “missing self” recognition to receptor biology, cellular diversity, and translational advances, highlighting NK cells’ evolution into modern immunotherapy.
Andreas Lundqvist +7 more
wiley +1 more source
ABSTRACT While transplantation outcomes are closely linked to HLA compatibility, minor histocompatibility antigens (mHAgs)—peptides embedded in HLA molecules bearing amino acid differences within the donor/recipient pair—also contribute to T‐cell alloreactivity, especially in HLA‐matched pairs.
Adèle Dhuyser +6 more
wiley +1 more source
Allorecognition is a key factor in Dictyostelium development and sociality. It is mediated by two polymorphic transmembrane proteins, TgrB1 and TgrC1, that contain extracellular immunoglobulin domains.
Shigenori Hirose +3 more
core +1 more source

