Results 61 to 70 of about 2,738 (186)
ABSTRACT Microvascular inflammation (MVI) in kidney allografts in the absence of detectable donor‐specific anti‐HLA antibodies (DSA) is increasingly recognised as a cause of premature graft failure following kidney transplantation. Potential mechanisms include NK cell alloreactivity mediated by recognition of mismatched HLA class I molecules (missing ...
Laura Knödl +8 more
wiley +1 more source
Allorecognition and the alloresponse: clinical implications
AbstractThe artificial transfer of tissues or cells between genetically diverse individuals elicits an immune response that is adaptive and specific. This response is orchestrated by T lymphocytes that are recognizing, amongst others, major histocompatibility complex (MHC) molecules expressed on the surface of the transferred cells.
Afzali, B +2 more
openaire +3 more sources
ABSTRACT Aim Maternal excess adiposity (i.e., overweight/obesity) is linked to impaired uteroplacental perfusion, compromised placental development, and increased risk of adverse pregnancy outcomes. Inflammation and immune dysregulation accompanying excess adiposity may disrupt leukocyte‐mediated tissue remodeling and immunoregulation, contributing to ...
Christian J. Bellissimo +11 more
wiley +1 more source
Fungal social barriers: to fuse, or not to fuse, that is the question
Cell fusion takes place in all domains of life and contributes greatly to the formation of complex multicellular structures. In particular, many fungi, such as the filamentous Neurospora crassa, rely on conspecific somatic cell fusion to drive the ...
A. Pedro Gonçalves, N. Louise Glass
doaj +1 more source
ABSTRACT The ascidian Boytryllus schlosseri is a marine chordate that thrives under conditions of anthropogenic climate change. The B. schlosseri expressed proteome contains unusually high levels of proteins adducted with 4‐hydroxy‐2‐nonenal (HNE). HNE represents a prominent posttranslational modification resulting from oxidative stress.
Dietmar Kültz +6 more
wiley +1 more source
The Role of Phyllosphere Microbes and Viruses in Biocontrol of Pathogenic Fungi
Foliar microbiota employ multiple ecological strategies to inhibit fungal pathogens in the phyllosphere, including resource competition, production of antifungal metabolites, contact‐dependent killing, modulation of plant innate immunity and mycovirus‐mediated suppression.
Li Bi +3 more
wiley +1 more source
Sponges, despite their simple body plan, discriminate between self and nonself with remarkable specificity. Sponge grafting experiments simulate the effects of natural self or nonself contact under laboratory conditions.
Laura F. Grice, Bernard M. Degnan
doaj +1 more source
The Invisible Lens: Why Theoretical Models Are Essential for Interpreting Immune Phenomena
ABSTRACT Immunology progresses not merely by accumulating data but by evolving the conceptual lenses through which those data are interpreted; yet for six decades the self–non‐self/infectious‐non‐self (SNS/INS) paradigm—casting allogeneity as activating signal and ‘self’ as intrinsically tolerogenic—has dominated research design, peer review and ...
Masoud H. Manjili
wiley +1 more source
Immunobiology of compound ascidians, with particular reference to Botryllus schlosseri: state of art [PDF]
The phylogenetic position of invertebrate chordates closely related to vertebrates explains the increasing interest towards tunicate immunobiology. Most of the tunicates are ascidians which, like all other invertebrates, rely only on innate immunity for ...
L Ballarin
doaj +1 more source
Lessons in modularity: the evolutionary ecology of colonial invertebrates
Benthic colonial invertebrates share with higher plants a modular construction and a sessile adult life. Both types of organism show parallel evolutionary responses to common selective forces, but in contrast to the long-established focus on plants ...
Roger N. Hughes
doaj +1 more source

