Results 61 to 70 of about 15,644 (230)

Evaluation of alloxan on induction of diabetes in albino rats

, 2019
Background: Alloxan-induced diabetes model is used as a “study tool” to elucidate the pathophysiology of the disease and much more as a “search engine” for antidiabetic compounds with better therapeutic characteristics. It was the first agent used in the
Mishra, A. N., ., Soni
core   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, Volume 4, Issue 2, Page 327-342, April 2026.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Hypoglycaemic effect of comatin, an antidiabetic substance separated from Coprinus comatus broth, on alloxan-induced-diabetic rats

, 2010
Comatin, an inhibitor of the non-enzymatic glycosylation (NEG) reaction, was isolated from Coprinus comatus fermentation broth by macroporous resin separation, followed by chromatographic purification using a C18 reversed-phase column.
Ding, Zhongyang, Lu, Zhaoxin, Zhang, Kechang, Bie, Xiaomei, Wang, Yuhong, Lu, Yingjian, Lv, Fengxia, Lu, ZX, Wang, Feng   +8 more
core   +1 more source

Hypoglycemic Properties of Oxovanadium (IV) Coordination Compounds with Carboxymethyl-Carrageenan and Carboxymethyl-Chitosan in Alloxan-Induced Diabetic Mice [PDF]

, 2011
In order to avoid low absorption, incorporation, and undesirable side effects of inorganic oxovanadium compounds, the antidiabetic activities of organic oxovanadium (IV) compounds in alloxan-induced diabetic mice were investigated.
Qin, Song, Yipeng Wang, Wang, Yipeng, Yuetao Yi, Hongyu Zhang, Dawei Feng, Yi, Yuetao, Zhang, Hongyu, Feng, Dawei, Song Qin   +9 more
core   +1 more source

Antidiabetic Activity Of Gladiolus Psittascinus In Alloxan Induced Diabetic Rats.

, 2008
The methanol extract of Gladiolus Psittascinus bulb was evaluated for its antidiabetic activities in alloxan-induced diabetic rats. Blood glucose levels of the glucose loaded and alloxan-induced diabetic rats were estimated over 180 minutes using the O ...
Adediwura, F-J, F-J Adediwura, A Kio, Kio, Abo, Adediwura, Fred-Jaiyesimi, Kio, A   +5 more
core   +3 more sources

Porang (Amorphophallus oncophyllus) tuber extract improved the histopathological features of diabetic rat (Rattus norvegicus) testicles

Ovozoa: Journal of Animal Reproduction
This study aims to determine the effect of porang (Amorphophallus oncophyllus) tuber extract on the histopathological features of the testicle of alloxan induced rats (Rattus norvegicus). Thirty male rats were randomly divided into six groups.
Dwi Puspa Sukma Viranda, Rochmah Kurnijasanti, Kadek Rachmawati, Iwan Sahrial Hamid, Pudji Srianto, Hani Plumeriastuti, Lita Rakhma Yustinasari   +6 more
doaj   +1 more source

Effects of Diet Strategy and Nutrients on the Progression and Prevention of Diabetic Cardiomyopathy: A Narrative Review

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Dietary strategies modulate the progression of diabetic cardiomyopathy by targeting oxidative stress, inflammation, mitochondrial dysfunction, and myocardial fibrosis. Specific nutrients and bioactive compounds, as well as caloric restriction, improve myocardial metabolism and redox balance, whereas ketogenic diets exert time‐dependent beneficial or ...
Wen‐hui Deng, Kai‐xuan Lin, Abdallah Iddy Chaurembo, Francis Chanda, Yuan Li, Li‐Dan Fu, Hao‐Dong Cui, Xin‐Yue Tong, Chi Shu, Han‐Bin Lin   +9 more
wiley   +1 more source

Exploring the antidiabetic potential of Octhochloa compressa: a comprehensive study on chemical profiling, in vitro, in vivo and in silico pharmacological properties

Frontiers in Pharmacology
Diabetes can lead to various health complications but can be managed with medication, diet, lifestyle changes, and certain medicinal plants with antidiabetic properties. Octhochloa compressa, a plant native to arid regions with a history of medicinal use,
Jawaria Aslam, Jawaria Aslam, Mirza Imran Shahzad, Hanan Y. Aati, Kashif-ur-Rehman Khan, Maria Aslam, Athar Jamal, Umar Farooq, Bilal Ahmad Ghalloo   +8 more
doaj   +1 more source

The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits

Scientific Papers Animal Science and Biotechnologies, 2023
The present experiment was intended to test the hypoglycemiant effect of an alcoholic extract of roots or of the fruit seeds from “in vitro” regenerated Momordica charantia Linn. plants grown at USAMVB Timisoara.
Horia Sărăndan, Dorica Botău, Iosif Ianculov, Florina Radu, Olga Rada, Doru Morar, Mihai Sărăndan, Maria Șerb, Adela Anghel   +8 more
doaj  

Alloxan Diabetes in Mice

Experimental Biology and Medicine, 1948
SummaryThe most effective dose and route of administration of alloxan were found to be 100 mg/kilo injected into the tail vein of the mouse. Fifty mice treated in this way all had blood sugar levels greater than 300 mg% 48 hours later. There were no mortalities.Fasting before the intraperitoneal injection of alloxan increased the mortality in mice ...
openaire   +2 more sources