Results 51 to 60 of about 10,812 (185)

Pengaruh Teh Hijau Terhadap Kadar Gula Darah dan MDA Serum Mencit Diabetes

open access: yesJurnal Ilmu Kesehatan Indonesia, 2020
Abstrak Diabetes melitus merupakan penyakit metabolik kronik yang ditandai dengan hiperglikemia yang jika terjadi secara terus-menerus akan menghasilkan radikal bebas berlebihan yang berperan dalam komplikasi diabetes.
Rizka Karima Husfa   +2 more
doaj   +1 more source

THE EFFECT OF BLACK CUMIN SEED (Nigella Sativa L.) EXTRACT TO ALLOXAN INDUCES PANCREATIC TISSUE CATALASE ENZYME ACTIVITY OF MALE WISTAR RATS (Rattus norvegicus)

open access: yesJurnal Ilmiah Kedokteran Wijaya Kusuma, 2018
Alloxan causes the formation of reactive oxygen through the reduction process of alloxan (dialuric acid) in the β cells of pancreas. Free radicals cause damage  and decrease catalase enzyme activity.
qonita achmad   +2 more
doaj  

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 7, Page 1277-1291, July 2026.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

open access: yesFood Safety and Health, Volume 4, Issue 3, Page 542-560, July 2026.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar   +10 more
wiley   +1 more source

SIFAT HIPOGLISEMIK PAKAN TINGGI PROTEIN KEDELAI PADA MODEL DIABEIK INDUKSI ALLOXAN [Hypoglicemic Property of a High-Protein Soybean Based Feed in Model alloxan Induced Diabetic]

open access: yesJurnal Teknologi dan Industri Pangan, 2001
Hypoglicemic properties of soybean protein were evaluated in alloxan-induced diabetic rats. Twenty eight mature male Sprague Dawley (SD) rats (250-300g) were used and divided into four groups of seven rats. They were: 1) Placebo Standars (PS); 2) Alloxan
C. Retnaningsih 1)   +2 more
doaj  

Porang (Amorphophallus oncophyllus) tuber extract improved the histopathological features of diabetic rat (Rattus norvegicus) testicles

open access: yesOvozoa: Journal of Animal Reproduction
This study aims to determine the effect of porang (Amorphophallus oncophyllus) tuber extract on the histopathological features of the testicle of alloxan induced rats (Rattus norvegicus). Thirty male rats were randomly divided into six groups.
Dwi Puspa Sukma Viranda   +6 more
doaj   +1 more source

Oleanolic Acid Ameliorates Hepatic Lipid Metabolism and Autophagy in Type 2 Diabetic Mice via the STAT3 Signaling Pathway

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
This study demonstrates that oleanolic acid (OA) may ameliorate type 2 diabetes mellitus (T2DM) by modulating hepatic lipid metabolism and autophagy in a manner concomitant with STAT3 phosphorylation. Specifically, OA downregulates fatty acid synthesis/uptake‐related proteins (SREBP‐1, ACC, CD36), upregulates fatty acid β‐oxidation‐related protein ...
Zirui Ji   +7 more
wiley   +1 more source

Exploring the antidiabetic potential of Octhochloa compressa: a comprehensive study on chemical profiling, in vitro, in vivo and in silico pharmacological properties

open access: yesFrontiers in Pharmacology
Diabetes can lead to various health complications but can be managed with medication, diet, lifestyle changes, and certain medicinal plants with antidiabetic properties. Octhochloa compressa, a plant native to arid regions with a history of medicinal use,
Jawaria Aslam   +8 more
doaj   +1 more source

The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
The present experiment was intended to test the hypoglycemiant effect of an alcoholic extract of roots or of the fruit seeds from “in vitro” regenerated Momordica charantia Linn. plants grown at USAMVB Timisoara.
Horia Sărăndan   +8 more
doaj  

Alloxan Diabetes in Mice

open access: yesExperimental Biology and Medicine, 1948
SummaryThe most effective dose and route of administration of alloxan were found to be 100 mg/kilo injected into the tail vein of the mouse. Fifty mice treated in this way all had blood sugar levels greater than 300 mg% 48 hours later. There were no mortalities.Fasting before the intraperitoneal injection of alloxan increased the mortality in mice ...
openaire   +2 more sources

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