Results 31 to 40 of about 9,791 (186)

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, Volume 9, Issue 7, Page 1277-1291, July 2026.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Ammodaucus leucotrichus Coss. & Durieu: Antihyperglycemic activity via the inhibition of α-amylase, α-glucosidase, and intestinal glucose absorption activities and its chemical composition. [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2022
Context: Ammodaucus leucotrichus commonly known as a ‘Kamune es sufi or akâman’ in Morocco, is used to treat many diseases including diabetes. Aims: To investigate the antihyperglycemic activity of an aqueous extract of fruits A.
Saliha Bouknana, Nour Elhouda Daoudi, Mohamed Bouhrim, Abderrahim Ziyyat, Abdelkhaleq Legssyer, Hassane Mekhfi, Mohamed Bnouham   +6 more
doaj  

Peculiarities of ionoregulatory renal function of rats in the dynamics of experimental diabetes mellitus development

Mìžnarodnij Endokrinologìčnij Žurnal, 2023
Background. The purpose of the research was to study the peculiarities of ionoregulatory renal function in the dynamics of alloxan-induced experimental diabetes mellitus. Materials and methods.
О.А. Olenovych
doaj   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, Volume 4, Issue 3, Page 542-560, July 2026.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source

ANTIDIABETIC ACTIVITY TEST USING AMLA FRUIT (PHYLLANTHUS EMBLICA L) EXTRACT IN ALLOXAN-INDUCED BALB/C MICE

Journal of Vocational Health Studies, 2019
Background: The content of secondary metabolites in amla (phyllanthus emblica L.) such as flavonoids and phenols have the potential as an antioxidant.
Putu Lakustini Cahyaningrum, Sang Ayu Made Yuliari, Ida Bagus Putra Suta   +2 more
doaj   +1 more source

The antioxidant and antidiabetic activity of the Arabian balsam tree “Commiphora gileadensis” in hyperlipidaemic male rats

Journal of Taibah University for Science, 2020
The leaf and twig aqueous extracts of Arabian balsam tree (Commiphora gileadensis) were tested to protect against alloxan-induced hyperglycaemia in hypercholesterolemic male rats.
Haddad A. El Rabey, Abdulbasit I. Al-Sieni, Madeha N. Al-Seeni, Mohammed A. Alsieni, Adel I. Alalawy, Fahad M. Almutairi   +5 more
doaj   +1 more source

Oleanolic Acid Ameliorates Hepatic Lipid Metabolism and Autophagy in Type 2 Diabetic Mice via the STAT3 Signaling Pathway

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
This study demonstrates that oleanolic acid (OA) may ameliorate type 2 diabetes mellitus (T2DM) by modulating hepatic lipid metabolism and autophagy in a manner concomitant with STAT3 phosphorylation. Specifically, OA downregulates fatty acid synthesis/uptake‐related proteins (SREBP‐1, ACC, CD36), upregulates fatty acid β‐oxidation‐related protein ...
Zirui Ji, Yuanfeng Huang, Xiangjin Pu, Jinqing Feng, Yiwen Liao, Wanfen Lin, Qing Zhu, Weixuan Wang   +7 more
wiley   +1 more source

Detoxification of Alloxan by Borate.

Experimental Biology and Medicine, 1951
ConclusionBorate greatly accelerates the conversion of alloxan to alloxanic acid. This observation provides an explanation for its protective effect against alloxan diabetes.
D, SELIGSON, H, SELIGSON
openaire   +2 more sources

Comprehensive Chemical and Biological Evaluation of Rosa damascena Plant Parts and Industrial Residues Using FTIR‐ATR and LC–MS/MS

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Rosa damascena flowers, buds, leaves, branches, and hydrodistillation by‐products were investigated using FTIR‐ATR, LC–MS/MS, and a series of biological assays. The integrated approach highlighted the chemical diversity and bioactive potential of both plant materials and industrial processing residues, supporting their sustainable valorization ...
Burak Bayrak, Hafize Yuca, Yasemin Beyza Budak, Satuk Buğra Alkuyruk, Elif Beyza Özer, Gülnur Ekşi Bona, Bilge Aydın, Mehmet Karadayı, Yusuf Gülşahin, Alptuğ Atila, Gamze Göger, Songul Karakaya   +11 more
wiley   +1 more source

Artikel Review: Pengaruh Pemberian Induksi Aloksan Terhadap Gula Darah Tikus

Indonesian Journal of Pharmaceutical Education
Diabetes mellitus is known as a condition where metabolic disorders occur accompanied by increased blood sugar levels in the body. Antidiabetic agent testing was developed using experimental animals and involves chemical components that have diabetogenic
Ni Luh Wayan Eva Wulandari, Ni Nyoman Wahyu Udayani, Ni Luh Kade Arman Anita Dewi, Ginza Afriyanchika Putri Triansyah, Ni Putu Eka Mahita Kumari Dewi, Ida Ayu Putu Widiasriani, Anak Agung Sagung Sri Prabandari   +6 more
doaj   +1 more source