Results 121 to 130 of about 1,621,772 (233)

Preparação de sais de isotiourônio as partir de brometos alílicos e tioureias: avaliação da atividade antitumoral e aplicações na síntese de 2-iminotiazolidinas e derivados [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.Este trabalho apresenta o desenvolvimento de métodos simples e eficientes para a síntese de ...
Ferreira, Misael
core  

A Ruthenium(CAAC‐5) Olefin Metathesis Catalyst for Bioconjugation

Angewandte Chemie International Edition, EarlyView.
The aqueous instability of ruthenium catalysts restricts olefin metathesis in biological media. A Ru(CAAC‐5) complex bearing an aniline handle is reported that remains active under biologically relevant conditions and enables bioconjugation to proteins, peptides, and an artificial metalloenzyme, providing a robust platform for olefin metathesis in ...
Damian Alexander Graf, Mikhail Boym, María Álvarez, Tsvetan Kardashliev, Thomas R. Ward   +4 more
wiley   +1 more source

SÍNTESE E AVALIAÇÃO DA ATIVIDADE CITOTÓXICA DE DERIVADOS DO EUGENOL CONTENDO NÚCLEOS 1,2,3-TRIAZÓLICOS

Química Nova
Eugenol is an aromatic compound found in several plant species. It presents important biological activities including cytotoxicity. In this paper, it is described the synthesis and the evaluation of the cytotoxic activity of eugenol derivatives bearing 1,
Poliana Aparecida Rodrigues Gazolla, Róbson Ricardo Teixeira, Adalberto Manoel da Silva, Boniek Gontijo Vaz, Géssica Adriana Vasconcelos, Raoni Pais Siqueira, Victor Hugo Sousa Gonçalves, Higor Sette Pereira, Gustavo Costa Bressan   +8 more
doaj   +1 more source

Rearrangement of Allyl Homoallyl Ethers to γ,δ-Unsaturated Carbonyl Compounds Catalyzed by Iridium Complexes

, 2016
Iridium complexes were found to promote the conversion of allyl homoallyl ethers to γ,δ-unsaturated carbonyl compounds. For example, treatment of 1-allyl-1-allyloxycyclohexane in the presence of catalytic amounts of [Ir(cod)Cl]2, PCy3, and Cs2CO3 in ...
Yasutaka Ishii (2209069), Takashi Higashino (3063294), Satoshi Sakaguchi (2006989)   +2 more
core   +1 more source

Non-C 2 symmetric chiral ligand dictating allyl-allyl coupling

Nature Communications
Enantioselective synthesis of chiral compounds is of high interest due to their importance in organic chemistry, medicinal chemistry, life science, and materials science.
Zhengshuai Xu, Hui Qian, Shengming Ma
doaj   +1 more source

The Effects of S-Allyl-Cysteine and Cannabidiol on Cerebral and Retinal Neurovascular Integrity and Cognitive Function in Type 2 Diabetes

Type 2 diabetes (T2D) induces cognitive dysfunction through neurovascular, inflammatory, and oxidative mechanisms. This thesis explores the therapeutic potential of S-allyl-cysteine (SAC) and cannabidiol (CBD) in mitigating these pathophysiologies ...
Maimuna Majimbi (23536441)
core  

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Design, synthesis, and biological evaluation of quinolin-2-one/thiazole hybrids as multi-targeted antiproliferative agents inducing caspase-dependent apoptosis. [PDF]

Sci Rep
Al-Wahaibi LH, Alzahrani AYA, Bräse S, Tawfeek HN, Youssif BGM.   +4 more
europepmc   +1 more source

QUANTITATION OF ALLYL ESTERS, LINALOOL, CITRAL, AND LINALYL ACETATE IN YOGURT AND SOFT DRINKS BY MEANS OF GC-MS

The pineapple and tropical fruit flavor of fruit yogurts and soft drinks is often supported by the addition of allyl esters - especially allyl hexanoate [1].
Sommerfeld, Frederike, Esslinger, Susanne, Gabler, Anna Maria, Stupak, Michal, Bönick, Josephine, Richter, Annemarie   +5 more
core  

Garlic-derived allyl sulfides attenuate house dust mite-induced allergic airway inflammation associated with reduced PI3K/NF-κB signaling. [PDF]

Front Pharmacol
Liu HC, Liu KF, Hour MJ, Hsieh CC, Li WS, Lee HZ, Tsai JC.   +6 more
europepmc   +1 more source