Results 141 to 150 of about 7,225 (307)

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Occupational Contact Urticaria, Protein Contact Dermatitis and Concomitant Airway Diseases in the Finnish Register of Occupational Diseases in 2005–2020: Main Causes and Occupations at Risk

Contact Dermatitis, EarlyView.
This Finnish registry study shows that concomitant occupational asthma and rhinitis are common in patients with occupational contact urticaria or protein contact dermatitis, often sharing the same exposure. When evaluating occupational immediate allergy, both skin and airway symptoms should be considered.
Ville Ojanen, Liisa Airaksinen, Hille Suojalehto, Kirsi Koskela, Maria Pesonen   +4 more
wiley   +1 more source

Characterisation of a cold‐adapted, thermostable glucokinase from psychrophilic Pseudoalteromonas sp. AS‐131 reveals how the enzyme achieves high thermal stability without loss of cold adaptation

The FEBS Journal, EarlyView.
We investigated glucokinase from the psychrophilic Pseudoalteromonas sp. AS‐131 (PsGK), which was isolated from the Antarctic Ocean. Biochemical studies revealed that PsGK is a cold‐adapted enzyme with high thermal stability, in contrast to general cold‐adapted enzymes, which have low thermal stability.
Akane Yato, Yuki Kato, Fuyuko Hayashi, Rio Asaka, Atsuko Ogawa, Tokuro Oda, Sayaka Tsuji, Masashi Unno, Nobuaki Soh, Keiichi Watanabe, Masaki Horitani   +10 more
wiley   +1 more source

Discovery of a cryptic aminoacidic triad involved in the temperature adaptation of GH1 enzymes

The FEBS Journal, EarlyView.
Cold‐active enzymes retain high catalytic activity at low temperatures but are characterized by thermal instability, a behavior not fully understood. Comparison between a cold‐active GH1 and its mesophilic counterparts highlights the role of a three‐residue motif (W‐M‐F) in conferring structural stability to a mesophilic GH1.
Stefania Digiovanni, Gabriel Oanca, Marco Orlando, Marina Lotti, Johan Åqvist, Marco Mangiagalli   +5 more
wiley   +1 more source

GeARF5/GeIAA33‐GeSWEET14 module balances the secondary metabolic biosynthesis to increase the yield and quality in Gastrodia elata

Journal of Integrative Plant Biology, EarlyView.
Auxin signaling regulates the formation of vegetative propagation corms in Gastrodia elata by regulating sugar‐acid interconversion, which in turn regulates polysaccharide and starch biosynthesis as well as biosynthesis of the bioactive metabolite gastrodin.
Qun Liu, Zhiqing Wu, Yugang Gao, Yue Xu, Pu Zang, Xinyu Yang, Yan Zhao, Pan Liao, Benoît Boachon, Guoyin Kai   +9 more
wiley   +1 more source

OsCPN10a, cooperating with OsCPN20 and OsHSP60‐3B negatively regulate ABA signaling and enhance seed storability in rice

Journal of Integrative Plant Biology, EarlyView.
Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao, Yidong Wei, Yongsheng Zhu, Kunyang Li, Ting Chen, Shuai Zhao, Fangxi Wu, Jinlan Wang, Pengbo Yu, Hongguang Xie, Liping Chen, Qiuhua Cai, Huaan Xie, Jianfu Zhang   +13 more
wiley   +1 more source

Alternative Protein Sources in Poultry and Pig Nutrition—A Review

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Proteins are an essential nutrient for the viability of all animals, enabling organisms to grow, regenerate and defend themselves against pathogenic organisms. Soybean and soybean‐based materials are commonly used to supplement protein in animal nutrition.
Lukáš Čumplík, Dana Zálešáková, Jakub Novotný, Lenka Kudlová, Leoš Pavlata, Ondřej Šťastník   +5 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Enhancement of sorghum biomass hydrolysis by addition of amylases to an ionic liquid-based deconstruction process. [PDF]

BMC Res Notes
Islam MT, Pidatala VR, Baidoo EEK, Wolski P, Choudhary H, Putnam DH, Hutmacher R, Atim J, Scown CD, Scheller HV, Simmons BA, Gladden JM, Rodriguez A.   +12 more
europepmc   +1 more source