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Alpha-gal syndrome [PDF]

Chinese Medical Journal
What is alpha-gal?\u2022 Alpha-gal (galactose-\u3b1-1,3-galactose) is a sugar molecule found in most mammals.\u2022 Alpha-gal is not found in fish, reptiles, birds, or people.\u2022 Alpha-gal can be found in meat (for example, pork, beef, rabbit, lamb ...
Mengyuan Zhan, Shaohui Chen, Tengda Xu, Jia Yin, Hao Li, Zhouxian Pan, Ning Cui, Liping Wen, Xiangxiang Pan   +8 more
doaj   +8 more sources

Mysterious Allergy Caused by Tick Bite: Alpha-Gal Syndrome [PDF]

Türkiye Parazitoloji Dergisi
Alpha-Gal syndrome (AGS) manifests as an intricate allergic response characterised by the formation of specific immunoglobulin E (IgE) antibodies targeting a carbohydrate termed galactose-a-1.3-galactose (a-Gal).
Muhammed Nalçacı
doaj   +2 more sources

Alpha‐gal syndrome—Food or drug allergy: A case report

Clinical Case Reports, 2023
Key Clinical Message Alpha‐gal syndrome is an immunoglobulin E‐mediated hypersensitivity characterized by delayed allergic reactions to ingested products containing alpha‐gal carbohydrate.
Marina Božan, Vesna Vukičević Lazarević, Ivan Marković, Jadranka Morović‐Vergles, Joško Mitrović   +4 more
doaj   +2 more sources

Antibody production and tolerance to the α-gal epitope as models for understanding and preventing the immune response to incompatible ABO carbohydrate antigens and for α-gal therapies

Frontiers in Molecular Biosciences, 2023
This review describes the significance of the α-gal epitope (Galα-3Galβ1-4GlcNAc-R) as the core of human blood-group A and B antigens (A and B antigens), determines in mouse models the principles underlying the immune response to these antigens, and ...
Uri Galili
doaj   +1 more source

Allergic Reactions and Immunity in Response to Tick Salivary Biogenic Substances and Red Meat Consumption in the Zebrafish Model

Frontiers in Cellular and Infection Microbiology, 2020
Ticks are arthropod ectoparasite vectors of pathogens and the cause of allergic reactions affecting human health worldwide. In humans, tick bites can induce high levels of immunoglobulin E antibodies against the carbohydrate Galα1-3Galβ1-(3)4GlcNAc-R (α ...
Marinela Contreras, Iván Pacheco, Pilar Alberdi, Sandra Díaz-Sánchez, Sara Artigas-Jerónimo, Lourdes Mateos-Hernández, Lourdes Mateos-Hernández, Margarita Villar, Alejandro Cabezas-Cruz, José de la Fuente, José de la Fuente   +10 more
doaj   +1 more source

GAL-Repository/EDA_Stuff: v1.0.2

, 2022
Full Changelog: https://github.com/GAL-Repository/EDA_Stuff/commits/v1.0.
GAL-Repository, Mauricio Rosales-Rivera
core   +1 more source

Alpha-gal syndrome – A case report of tick-borne anaphylactic shock

European Journal of Case Reports in Internal Medicine, 2023
The most common cause of vasoplegic shock in critical care is sepsis. However, although rarely and only in specifically sensitised individuals previously bitten by a tick, red meat may provoke a delayed allergic reaction called an alpha-gal syndrome.
Jiri Muller, Jaroslav Radej, Miroslav Kriz, Eliska Hunkova, Jan Kasparek, Martin Matejovic   +5 more
doaj   +1 more source

Association between lone star tick bites and increased alpha-gal sensitization: evidence from a prospective cohort of outdoor workers

Parasites & Vectors, 2020
Background Alpha-gal is an oligosaccharide implicated in delayed anaphylaxis following red meat consumption. Exposure to tick bites has been correlated with development of an allergic response to alpha-gal.
Cedar L. Mitchell, Feng-Chang Lin, Meagan Vaughn, Charles S. Apperson, Steven R. Meshnick, Scott P. Commins   +5 more
doaj   +1 more source

Diagnostic validity of specific immunoglobulin E levels to alpha-gal in alpha-gal syndrome: a cross-sectional analysis

Allergy, Asthma & Clinical Immunology, 2023
Background The diagnosis of Alpha-gal Syndrome (AGS) is based on the presence of symptoms after being exposed to potential sources of alpha-gal together with values ​​of specific IgE (sIgE) to alpha-gal ≥ 0.1 kUA/L or ≥ 0.35 kUA/L.
Adrián Germán-Sánchez, Ana Alonso-Llamazares, Fernando García-González, Bakai Matala-Ahmed, Ceny Solani Melgar-Reyes, Ignacio Antepara-Ercoreca   +5 more
doaj   +1 more source

Alpha-gal syndrome and the gastrointestinal reaction: a narrative review [PDF]

Frontiers in Allergy
Dorothea K Thompson
exaly   +2 more sources