Results 21 to 30 of about 948,383 (242)

Is Zebrafish a Good Model for the Alpha-Gal Syndrome? [PDF]

FASEB J
The alpha-Gal syndrome (AGS) is an underdiagnosed tick-borne allergy characterized by both immediate and delayed IgE-mediated anaphylactic reactions to the galactose-alpha-1,3-galactose (alpha-Gal) epitope. Common manifestations include gastrointestinal,
Vaz-Rodrigues R, de la Fuente J.
europepmc   +2 more sources

Characterization of Properties and Transglycosylation Abilities of Recombinant α-Galactosidase from Cold-Adapted Marine Bacterium Pseudoalteromonas KMM 701 and Its C494N and D451A Mutants

Marine Drugs, 2018
A novel wild-type recombinant cold-active α-d-galactosidase (α-PsGal) from the cold-adapted marine bacterium Pseudoalteromonas sp. KMM 701, and its mutants D451A and C494N, were studied in terms of their structural, physicochemical, and ...
Irina Bakunina, Lubov Slepchenko, Stanislav Anastyuk, Vladimir Isakov, Galina Likhatskaya, Natalya Kim, Liudmila Tekutyeva, Oksana Son, Larissa Balabanova   +8 more
doaj   +1 more source

Tick Intrastadial Feeding and Its Role on IgE Production in the Murine Model of Alpha-gal Syndrome: The Tick “Transmission” Hypothesis

Frontiers in Immunology, 2022
Recent studies have provided strong evidence indicating that lone star tick bites are a cause of AGS (alpha-gal syndrome, also known as red meat allergy RMA) in humans.
L. Paulina Maldonado-Ruiz, Gunavanthi D. Boorgula, Donghun Kim, Sherry D. Fleming, Yoonseong Park   +4 more
doaj   +1 more source

Activation of Silent gal Genes in the lac-gal Regulon of Streptococcus thermophilus [PDF]

, 2001
Streptococcus thermophilus strain CNRZ 302 is unable to ferment galactose, neither that generated intracellularly by lactose hydrolysis nor the free sugar.
Vos, W.M., de, Kuipers, Oscar P.; id_orcid, Kuipers, Oscar P., van den Bogaard, P.T.C., Catzeddu, Pasquale,, Bogaard, Patrick T.C. van den, Vaughan, Elaine E., Bogaard, P.T.C., van den, Vaughan, E.E., Kuipers, Oscar P.,, Bogaard, Patrick T.C. van den,, Kuipers, O.P., Vaughan, Elaine E.,, Vos, Willem M. de, Vos, Willem M. de,, de Vos, W.M., Catzeddu, Pasquale, Catzeddu, P.   +17 more
core   +2 more sources

The Meat of the Matter: Understanding and Managing Alpha-Gal Syndrome

ImmunoTargets and Therapy, 2022
Jessica D Macdougall,1,2,* Kevin O Thomas,1,2,* Onyinye I Iweala1,2 1Department of Medicine, Thurston Arthritis Research Center, Division of Rheumatology, Allergy, and Immunology, Chapel Hill, NC, 27599, USA; 2Department of Pediatrics, University
Macdougall JD, Thomas KO, Iweala OI
doaj  

Alpha gal specific IgE positivity due to tick bites and red meat allergy: the first case report in Turkey

The Turkish Journal of Pediatrics, 2019
Galactose-alpha-1,3-galactose is a carbohydrate moiety found in the cell membranes of many organisms, commonly known as alpha-gal (α-Gal). This oligosaccharide is not found in the group of primates in which humans are involved.
Şennur Keleş, Mehmet Gündüz
doaj   +1 more source

Alpha-gal syndrome initially misdiagnosed as chronic spontaneous urticaria in a pediatric patient: a case report and review of the literature

Journal of Medical Case Reports, 2023
Introduction Delayed allergy to red meat, also termed alpha-gal syndrome, is increasingly reported in adults and African communities, while pediatric cases remain rare.
Felicitas Bellutti Enders, Marius Elkuch, Andreas Wörner, Kathrin Scherer Hofmeier, Karin Hartmann   +4 more
doaj   +1 more source

IgG to Galactose-Alpha-1,3-Galactose: Impact of Alpha-Gal IgE Sensitization, Blood Type, and Tick Bites

Antibodies
Background: Antibodies to galactose-alpha-1,3-galactose (alpha-gal), particularly the IgM and IgG isotypes, are abundant in human sera. These antibodies are known to be an important xenotransplantation barrier, but the full implications of these ...
Samuel M. Ailsworth, Matthew MacCallum, Nathan E. Richards, Lisa J. Workman, Pamela Schoppee Bortz, Thomas Makin, Thomas A. E. Platts-Mills, Jeffrey M. Wilson   +7 more
doaj   +1 more source

DataSheet_1_A novel monoclonal IgG1 antibody specific for Galactose-alpha-1,3-galactose questions alpha-Gal epitope expression by bacteria.docx

, 2022
The alpha-Gal epitope (α-Gal) with the determining element galactose-α1,3-galactose can lead to clinically relevant allergic reactions and rejections in xenotransplantation.
Andrew Flatley (13206537), Stefanie Eyerich (575059), Caspar Ohnmacht (12790790), Luisa Kreft (13206534), Neera Chakrapani (13206543), Regina Feederle (166063), Tilo Biedermann (116048), Aloys Schepers (193494), Christiane Hilger (7884023), Miriam Hils (6475274), Li Deng (442821), Konrad Fischer (6581888), Dierk Niessing (224204), Simon Blank (405509), Mahesh S. Desai (10175492), Kyra Swiontek (13196094), Mohammadali Khan Mirzaei (10732672), Michael Dittmar (13206540), Robert Janowski (411717), Carsten B. Schmidt-Weber (11714631)   +19 more
core   +1 more source

Streamlining the Detection of Human Thyroid Receptor Ligand Interactions with XL1-Blue Cell-Free Protein Synthesis and Beta-Galactosidase Fusion Protein Biosensors

Life, 2023
Thyroid receptor signaling controls major physiological processes and disrupted signaling can cause severe disorders that negatively impact human life.
J. Porter Hunt, Tyler J. Free, Jackelyn Galiardi, Kevin M. Watt, David W. Wood, Bradley C. Bundy   +5 more
doaj   +1 more source