Results 11 to 20 of about 5,907 (191)

Novel pyrrolizidine alkaloid [PDF]

, 1991
The present invention involves a purified bioactive compound of the formula: ##STR1## wherein at least one of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are H or an acyl having less than about five carbon atoms.
Elbein, Alan D., Tropea, Joseph E.
core   +1 more source

1,6-Cyclophellitol Cyclosulfates : A New Class of Irreversible Glycosidase Inhibitor [PDF]

, 2017
The essential biological roles played by glycosidases, coupled to the diverse therapeutic benefits of pharmacologically targeting these enzymes, provide considerable motivation for the development of new inhibitor classes.
Aerts, Johannes M.F.G., Artola, Marta, Breen, Imogen Z., Codée, Jeroen D.C., Davies, Gideon J., Ferraz, Maria J., Kuo, Chi Lin, Offen, Wendy A., Overkleeft, Herman S., Raich, Lluís, Rovira, Carme, Van Der Marel, Gijsbert A., Wu, Liang   +12 more
core   +9 more sources

The Santorini Volcanic Complex as a Valuable Source of Enzymes for Bioenergy

Energies, 2021
Marine microbial communities are an untapped reservoir of genetic and metabolic diversity and a valuable source for the discovery of new natural products of biotechnological interest.
Paraskevi N. Polymenakou, Paraskevi Nomikou, Haris Zafeiropoulos, Manolis Mandalakis, Thekla I. Anastasiou, Stephanos Kilias, Nikos C. Kyrpides, Georgios Kotoulas, Antoniοs Magoulas   +8 more
doaj   +1 more source

Impact of infection on the secretory capacity of the male accessory glands

International Brazilian Journal of Urology, 2009
INTRODUCTION: Studies that compare the impact of different infectious entities of the male reproductive tract (MRT) on the male accessory gland function are controversial.
M. Marconi, A. Pilatz, F. Wagenlehner, T. Diemer, W. Weidner   +4 more
doaj   +1 more source

Alpha-glucosidase Inhibitors

JPMA. The Journal of the Pakistan Medical Association, 2014
Alpha glucosidase inhibitors (AGIs) are a unique class of anti-diabetic drugs. Derived from bacteria, these oral drugs are enzyme inhibitors which do not have a pancreato -centred mechanism of action. Working to delay carbohydrate absorption in the gastrointestinal tract, they control postprandial hyperglycaemia and provide unquestioned cardiovascular ...
Sanjay Kalra, Jaikrit Bhutani
openaire   +3 more sources

Genome-wide identification and expression analysis of tomato glycoside hydrolase family 1 β-glucosidase genes in response to abiotic stresses

Biotechnology & Biotechnological Equipment, 2022
In plants, β-glucosidases (BGLUs) are important glycoside hydrolases involved in several biological phenomena, including the response to stresses via the activation of phytohormones and the release of alpha-hydroxy nitriles to protect against stresses ...
Jinpeng Wei, Qiusen Chen, Jiaxin Lin, Fengqiong Chen, Runan Chen, Hanlin Liu, Peiyu Chu, Zhiyong Lu, Shaozhe Li, Gaobo Yu   +9 more
doaj   +1 more source

GLP-1 receptor agonists or DPP-4 inhibitors: How to guide the clinician? [PDF]

, 2013
Pharmacological treatment of type 2 diabetes has been enriched during recent years, with the launch of incretin therapies targeting glucagon-like peptide-1 (GLP-1).
SCHEEN, André
core   +1 more source

RNAseq analysis of Cellvibrio japonicus during starch utilization differentiates between genes encoding carbohydrate active enzymes controlled by substrate detection or growth rate

Microbiology Spectrum, 2023
Bacterial utilization of starch is increasingly of interest as the importance and contributions of animal gut microbiomes become more defined. Consequently, identifying and characterizing the bacterial enzymes responsible for the degradation, transport ...
Cecelia A. Garcia, Jeffrey G. Gardner
doaj   +1 more source

Structure and Function Insight of the α-Glucosidase QsGH13 From Qipengyuania seohaensis sp. SW-135

Frontiers in Microbiology, 2022
The α-glucosidases play indispensable roles in the metabolic mechanism of organism, prevention, and treatment of the disease, and sugar hydrolysis, and are widely used in chemical synthesis, clinical diagnosis, and other fields.
Xingyu Zhai, Xingyu Zhai, Kaijuan Wu, Rui Ji, Yiming Zhao, Jianhong Lu, Zheng Yu, Xuewei Xu, Jing Huang   +8 more
doaj   +1 more source

Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism [PDF]

, 2016
Starch is a major energy store in plants. It provides most of the calories in the human diet and, as a bulk commodity, it is used across broad industry sectors.
Alison M. Smith, Andriotis, Andriotis, Aoki, Asano, Asano, Bak-Jensen, Banik, Birte Svensson, Blackwell, Boisson, Burn, Burton, Burton, Chandrasekar, Chavez Montes, Comparot-Moss, Daussant, Dinges, Fincher, Finnie, Frandsen, Gibbons, Hatzfeld, Hickes, Holdsworth, Ichinose, Kihara, Kim, Kolodziejek, Lagaert, Lee, Lee, MacGregor, Martin Rejzek, Mega, Michael D. Rugen, Moreno-Risueno, Møller, Nash, O'Brien, Rejzek, Ritchie, Robert A. Field, Ruzanski, Sissons, Slade, Smith, Smith, Sonnewald, Soussillane, Stanley, Tanaka, Vasilios M. E. Andriotis, Vriet, Wheeler, Winchester, Zeeman   +57 more
core   +2 more sources