Results 231 to 240 of about 3,445,082 (289)

Quercetin/chitosan-graft-alpha lipoic acid micelles: A versatile antioxidant water dispersion with high stability.

Carbohydrate Polymers, 2020
Natural active compounds with antioxidant properties and other potential health benefits, like quercetin (Qu), have aroused wide concern for developing bio-functional products.
Feng Shen, Haoquan Zhong, Wenjiao Ge, Junli Ren, Xiao-Hui Wang   +4 more
semanticscholar   +1 more source

ALSUntangled #79: alpha-lipoic acid

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Alpha-lipoic acid (ALA) is a naturally occurring fatty acid. It serves as an essential cofactor for enzymatic reactions in mitochondrial energy production, is a potent antioxidant and has anti-inflammatory effects, which are plausible mechanisms in slowing ALS progression.
Alaina Giacobbe, James Hiana, Olivia Wang, Michael Benatar, Paul Wicks, Javier Mascias Cadavid, Sartaj Jhooty, Christopher McDermott, Gary Pattee, Tulio Bertorini, Terry Heiman-Patterson, Dylan Ratner, Paul Barkhaus, Gregory Carter, Carlayne Jackson, Keelie Denson, Andrew Brown, Carmel Armon, Yuyao Sun, Andre Nguyen, Richard Bedlack, Xiaoyan Li   +21 more
openaire   +2 more sources

Alpha lipoic acid

The Netherlands Journal of Medicine, 2010
Background: Neuropathic pain is difficult to treat. We identified those studies in the literature in which the effectiveness of alpha lipoic acid as a treatment for neuropathic pain was evaluated.Methods: Systematic literature review. The databases MEDLINE and EMBASE were searched using the keywords "lipoic acid", "thioctic acid", "diabet*", and the ...
Mijnhout, G. S., Alkhalaf, A., Kleefstra, N., Bibo, H. J. G.   +3 more
openaire   +1 more source

Alpha‐lipoic acid: A possible pharmacological agent for treating dry eye disease and retinopathy in diabetes

Clinical and Experimental Pharmacology and Physiology, 2020
Alpha‐lipoic acid (ALA) is a naturally occurring dithiol micronutrient which acts as a cofactor for mitochondrial enzyme activity. Due to its potential antioxidant activity, it is considered as “universal antioxidant”.
T. Ajith
semanticscholar   +1 more source

Nitrogen-doped carbon quantum dots as a “turn off-on” fluorescence sensor based on the redox reaction mechanism for the sensitive detection of dopamine and alpha lipoic acid

, 2020
A simple and reliable fluorescence sensing strategy, which depends on the strong fluorescence emission of nitrogen-doped carbon quantum dots (N-CQDs) and efficient catalytic oxidation of tyrosinase (Tyr), was demonstrated for the sensitive detection of ...
Ruxia Zhang, Zhe-Feng Fan
semanticscholar   +1 more source

The effects of alpha-lipoic acid on diabetic myopathy

Journal of Endocrinological Investigation, 2017
Increased oxidative stress and impaired antioxidant defense are important mechanisms in the pathogenesis of diabetic myopathy. Since diabetes mellitus type 1 decreases muscle regeneration capacity the present study was designed to determine the influence of alpha-lipoic acid (ALA), a potent biological antioxidant, on the process of regeneration of ...
Jurišić Eržen, Dubravka, Starčević-Klasan, Gordana, Ivanac, Danijel, Peharec, Stanislav, Girotto, Dean, Jerković, Romana   +5 more
openaire   +4 more sources

Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study.

Endocrine, Metabolic & Immune Disorders - Drug Targets, 2020
BACKGROUND Alpha-lipoic acid (ALA) was tried in treatment of diabetic peripheral neuropathy (DPN) using different routes, doses and treatment durations.
M. El-Nahas, Ghada Elkannishy, Hala Abdelhafez, Enas T. Elkhamisy, Amr A. El-Sehrawy   +4 more
semanticscholar   +1 more source

Alpha-lipoic acid in the treatment of diabetic polyneuropathy

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2018
The issues of classification, pathogenesis, pathomorphology and treatment of diabetic polyneuropathy (DPN) are addressed. Pathogenetic mechanisms of the action of alpha-lipoic acid in treatment of DPN are justified. The authors present the results of randomized placebo-controlled trials of alpha-lipoic acid that revealed the high clinical efficacy and ...
E I, Chukanova, A S, Chukanova
openaire   +2 more sources

Alpha-lipoic acid improves sperm motility in infertile men after varicocelectomy: a triple-blind randomized controlled trial.

Reproductive Biomedicine Online, 2020
RESEARCH QUESTION Does supplementation with alpha-lipoic acid (ALA) enhance sperm parameters and/or the status of sperm lipid peroxidation and DNA fragmentation in men who have undergone microsurgical repair of a varicocele?
Behzad Abbasi, Newsha Molavi, M. Tavalaee, H. Abbasi, M. Nasr-Esfahani   +4 more
semanticscholar   +1 more source

Protective effects of alpha-lipoic acid on anxiety-like behavior, memory and prevention of hippocampal oxidative stress in methamphetamine-treated rats

Psychopharmacology, 2023
Hossein Mohammad-Pour Kargar, Hamid Noshiri   +1 more
semanticscholar   +1 more source