Results 41 to 50 of about 26,643 (286)
Lipid lowering effect of antioxidant alpha-lipoic acid in experimental atherosclerosis. [PDF]
, 2008 Accumulating data demonstrated that hypercholesterolemia and oxidative stress play an important role in the development of atherosclerosis. In the present study, a protective activity of alpha-lipoic acid; a metabolic antioxidant in hypercholesterolemic ...
Amom, Zulkhairi +9 more
core +2 more sources
Journal of Diabetes Research, 2015 After evaluating the prevalence of early endothelial dysfunction, as measured by means of reactive hyperemia in adolescents with type 1 diabetes, we started a 6-month, double-blind, randomized trial to test the efficacy of an antioxidant diet (± alpha ...
Andrea Scaramuzza +8 more
doaj +1 more source
74 Alpha Lipoic Acid Responsive Hypergeusia [PDF]
CNS Spectrums, 2019 AbstractIntroductionImprovement in hypergeusia in response to alpha lipoic acid treatment has not heretofore been described. Such a case is presented.MethodsCase Study: A 64 year old right handed nasute female noted the sudden onset of salty hypergeusia, about 200% saltier than foods should be.
Sarah E. Cormie, Alan R. Hirsch
openaire +1 more source
Effects of R-Alpha Lipoic Acid on HbA1c, Lipids and Blood Pressure in Type-2 Diabetics: A Preliminary Study [PDF]
, 2009 R-alpha lipoic acid (R-ALA) supplementation improves blood glucose in diabetic animals, but there have been no long-term clinical trials in humans testing its use for glucose control (HbA1c).
Hoffman, Elisa +3 more
core +2 more sources
Alpha lipoic acid posses dual antioxidant and lipid lowering properties in athersclerotic-induced New Zealand white rabbit [PDF]
, 2008 There is accumulating data demonstrated hypercholesterolemia and oxidative stress play an important role in the development of atherosclerosis.
Amom, Zulkhairi +6 more
core +1 more source
Mìžnarodnij Endokrinologìčnij Žurnal, 2012 The article deals with one of most common complications of diabetes mellitus — diabetic polyneuropathy. It is proved that alpha-lipoic acid is a drug of pathogenetic treatment of such pathology.
O.V. Bolshova, O.Ya. Samson
doaj +1 more source
Encapsulation of α-lipoic acid intochitosan and alginate/gelatin hydrogel microparticles and its in vitro antioxidant activity [PDF]
Hemijska Industrija, 2016 Alpha-lipoic acidis an organosulphur compound well-known for its therapeutic potential and antioxidant properties. However, the effective use of α-lipoic acid depends on biological plasma half-life and its preserving stability, which could be ...
Vidović Bojana B. +6 more
doaj +1 more source
Advanced Science, EarlyView.Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He +8 more
wiley +1 more source
Gut microbiota markers in obese adolescent and adult patients: Age-dependent differential patterns [PDF]
, 2018 Obesity levels, especially in children, have dramatically increased over the last few decades. Recently, several studies highlighted the involvement of gut microbiota in the pathophysiology of obesity. We investigated the composition of gut microbiota in
Alessandra Russo +15 more
core +2 more sources
Alpha-Lipoic Acid: Biological Mechanisms and Health Benefits. [PDF]
Antioxidants (Basel)Alpha-lipoic acid (ALA) is a bioactive molecule with significant health effects. The biological action of ALA has been ascribed to the characteristic antioxidant properties of the oxidized form (ALA) and its reduced counterpart the dihydrolipoic acid (DHLA) system.
Superti F, Russo R.
europepmc +4 more sources