Results 31 to 40 of about 4,718 (156)

Nicotinic receptor Alpha7 expression during mouse adrenal gland development. [PDF]

PLoS ONE, 2014
The nicotinic acetylcholine receptor alpha 7 (α7) is a ligand-activated ion channel that contributes to a diversity of cellular processes involved in development, neurotransmission and inflammation. In this report the expression of α7 was examined in the
Lorise C Gahring, Elizabeth Myers, Sierra Palumbos, Scott W Rogers   +3 more
doaj   +1 more source

Alpha7 neuronal nicotinic acetylcholine receptors are negatively regulated by tyrosine phosphorylation and Src-family kinases [PDF]

, 2005
Nicotine, a component of tobacco, is highly addictive but possesses beneficial properties such as cognitive improvements and memory maintenance. Involved in these processes is the neuronal nicotinic acetylcholine receptor (nAChR) alpha7, whose activation
Hoda, J. C., Huh, K H, Hoda, J C, Charpantier, E, Raggenbass, M, Allaman, Geraldine, Ogier, R, Raggenbass, Mario, Allaman, G, Charpantier, Eric, Fuhrer, Christian, Wiesner, A, Bertrand, Daniel, Wiesner, Andreas, Huh, K. H., Feuerbach, D, Ogier, Roch, Bertrand, D, Feuerbach, Dominik, Fuhrer, Christian; https://orcid.org/   +19 more
core   +1 more source

Alpha7 nAChR: pathogenesis and treatment of chemotherapy-induced neuropathy

, 2012
Oxaliplatin, unlike other platinum chemotherapic agents, does not result in significant renal impairment or ototoxicity, and it has only mild hematological and gastrointestinal toxicity.
C. Matera, M. De Amici, A. Pacini, C. De Micheli, C. Ghelardini, C. Dallanoce, L. Di Cesare Mannelli, M. Zanardelli   +7 more
core   +2 more sources

NAD+ biosynthesis ameliorates a zebrafish model of muscular dystrophy.

PLoS Biology, 2012
Muscular dystrophies are common, currently incurable diseases. A subset of dystrophies result from genetic disruptions in complexes that attach muscle fibers to their surrounding extracellular matrix microenvironment.
Michelle F Goody, Meghan W Kelly, Christine J Reynolds, Andre Khalil, Bryan D Crawford, Clarissa A Henry   +5 more
doaj   +1 more source

Identification of new bile alcohols, 5 beta-cholestane-3 alpha,7 alpha,24,26-tetrol, 5 beta-cholestane-3 alpha,7 alpha,25,26-tetrol, and 5 beta-cholestane-3 alpha,7 alpha,26,27-tetrol in human gallbladder bile.

Journal of Lipid Research, 1990
The nature of cholestanetetrols present as the glucurono-conjugates in human gallbladder bile was studied. Glucurono-conjugated bile alcohols were isolated by ion exchange chromatography and, after enzymatic hydrolysis, were fractionated by reversed ...
M Une, Y Shinonaga, N Matoba, S Kuroki, K Kihira, T Hoshita   +5 more
doaj   +1 more source

Nicotinic receptor alpha7 expression identifies a novel hematopoietic progenitor lineage. [PDF]

PLoS ONE, 2013
How inflammatory responses are mechanistically modulated by nicotinic acetylcholine receptors (nAChR), especially by receptors composed of alpha7 (α7) subunits, is poorly defined.
Lorise C Gahring, Elena Y Enioutina, Elizabeth J Myers, Gerald J Spangrude, Olga V Efimova, Todd W Kelley, Petr Tvrdik, Mario R Capecchi, Scott W Rogers   +8 more
doaj   +1 more source

Beneficial impacts of neuromuscular electrical stimulation on muscle structure and function in the zebrafish model of Duchenne muscular dystrophy

eLife, 2022
Neuromuscular electrical stimulation (NMES) allows activation of muscle fibers in the absence of voluntary force generation. NMES could have the potential to promote muscle homeostasis in the context of muscle disease, but the impacts of NMES on diseased
Elisabeth A Kilroy, Amanda C Ignacz, Kaylee L Brann, Claire E Schaffer, Devon Varney, Sarah S Alrowaished, Kodey J Silknitter, Jordan N Miner, Ahmed Almaghasilah, Tashawna L Spellen, Alexandra D Lewis, Karissa Tilbury, Benjamin L King, Joshua B Kelley, Clarissa A Henry   +14 more
doaj   +1 more source

Chemotherapy-induced neuropathy: involvement of the alpha7 nAChR subtype

, 2011
The limiting side effect of the chemotherapeutic agent oxaliplatin is its neurotoxicity, which promotes a neuropathic syndrome. In a rat model of oxaliplatin-induced neuropathy (2.4 mgkg-1 intraperitoneally, daily injected for 21 days), a dramatic ...
C. Matera, M. De Amici, A. Pacini, C. De Micheli, C. Ghelardini, C. Dallanoce, L. Di Cesare Mannelli, M. Zanardelli   +7 more
core   +2 more sources

α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect

Journal of Neuroinflammation, 2023
Depression is a common mental illness, which is related to monoamine neurotransmitters and the dysfunction of the cholinergic, immune, glutamatergic, and neuroendocrine systems.
Huiyang Liu, Xiaomei Zhang, Peng Shi, Jiyuan Yuan, Qiang Jia, Chao Pi, Tao Chen, Linjin Xiong, Jinglin Chen, Jia Tang, Ruxu Yue, Zerong Liu, Hongping Shen, Ying Zuo, Yumeng Wei, Ling Zhao   +15 more
doaj   +1 more source

The human alpha7 nicotinic acetylcholine receptor is a host target for the rabies virus glycoprotein

Frontiers in Cellular and Infection Microbiology
The rabies virus enters the nervous system by interacting with several molecular targets on host cells to modify behavior and trigger receptor-mediated endocytosis of the virion by poorly understood mechanisms.
Brittany C. V. O’Brien, Shelly Thao, Lahra Weber, Helen L. Danielson, Agatha D. Boldt, Karsten Hueffer, Maegan M. Weltzin   +6 more
doaj   +1 more source