Studying the function of α7 nicotinic acetylcholine receptor in Drosophila humoral immunity
Acetylcholine (ACh) is one the major neurotransmitters, whose role in mediating synaptic interactions between neurons in the central nervous system in vertebrates and invertebrates is well characterized.
Giulia Cattabriga +7 more
core
Target identification and validation of the alpha7 nicotinic acetylcholine receptor as a potential therapeutic target in retinal disease. [PDF]
Linn DM.
europepmc +1 more source
Potentials of Mean Force for Acetylcholine Unbinding from the Alpha7 Nicotinic Acetylcholine Receptor Ligand-Binding Domain [J. Am. Chem. Soc. 2006, 128, 3019−3026]
J. Andrew McCammon (12411) +1 more
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The wide use of antibiotics and the development of resistance is a major health concern and, despite their relatively severe side effects, aminoglycoside antibiotics are still used in clinics.
Krause R +3 more
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Unprecedented effect of vitamin D3 on T-cell receptor beta subunit and alpha7 nicotinic acetylcholine receptor expression in a 3-nitropropionic acid induced mouse model of Huntington's disease. [PDF]
Manjari S +5 more
europepmc +1 more source
We examined the potential expression and function of alpha7 nicotinic acetylcholine receptors (nAChRs) in leukocytes. RT-PCR with alpha7 specific primers revealed the presence of the receptor mRNA in leukocytes.
Villiger, Y. +7 more
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Alpha7 Nicotinic Acetylcholine Receptor Antagonists Prevent Meningitic Escherichia coli-Induced Blood-Brain Barrier Disruptions by Targeting the CISH/JAK2/STAT5b Axis. [PDF]
Gong Z +8 more
europepmc +1 more source
Cholinergic dysfunction-induced insufficient activation of alpha7 nicotinic acetylcholine receptor drives the development of rheumatoid arthritis through promoting protein citrullination via the SP3/PAD4 pathway. [PDF]
Lv C +12 more
europepmc +1 more source
Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor.
International audienceWe report that preapplication of ivermectin, in the micromolar range, strongly enhances the subsequent acetylcholine-evoked current of the neuronal chick or human alpha7 nicotinic acetylcholine receptors reconstituted in Xenopus ...
Buisson, Bruno +13 more
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The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia-reperfusion brain injury in mice. [PDF]
Hammarlund ME +7 more
europepmc +1 more source

