Results 111 to 120 of about 2,877 (196)

Kinetic properties and open probability of alpha7 nicotinic acetylcholine receptors.

, 2014
The alpha7 nicotinic acetylcholine receptor (nAChR) has some peculiar kinetic properties. From the literature of alpha7 nAChR-mediated currents we concluded that experimentally measured kinetic properties reflected properties of the solution exchange ...
Szabó, AK, Mike, Árpád, Vizi, E. Szilveszter, Pesti, Krisztina   +3 more
core   +1 more source

Target identification and validation of the alpha7 nicotinic acetylcholine receptor as a potential therapeutic target in retinal disease. [PDF]

Front Ophthalmol (Lausanne), 2023
Linn DM.
europepmc   +1 more source

α-Conotoxin ImI-modified polymeric micelles as potential nanocarriers for targeted docetaxel delivery to α7-nAChR overexpressed non-small cell lung cancer

Drug Delivery, 2018
A micelle system modified with α-Conotoxin ImI (ImI), a potently antagonist for alpha7 nicotinic acetylcholine receptor (α7-nAChR) previously utilized for targeting breast cancer, was constructed.
Dong Mei, Libo Zhao, Binlong Chen, Xiaoyan Zhang, Xiaoling Wang, Zhiying Yu, Xin Ni, Qiang Zhang   +7 more
doaj   +1 more source

Unprecedented effect of vitamin D3 on T-cell receptor beta subunit and alpha7 nicotinic acetylcholine receptor expression in a 3-nitropropionic acid induced mouse model of Huntington's disease. [PDF]

IBRO Neurosci Rep, 2023
Manjari S, Abraham SM, Poornima R, Chaturvedi RK, Maity S, Komal P.   +5 more
europepmc   +1 more source

Evaluating the suitability of nicotinic acetylcholine receptor antibodies for standard immunodetection procedures

, 2007
International audienceNicotinic acetylcholine receptors play important roles in numerous cognitive processes as well as in several debilitating central nervous system (CNS) disorders.
de Biasi, M., Marubio, L., Changeux, J.-P., Moser, N., Jones, I., Roth, U., Winzer-Serhan, U., Orr-Urtreger, A., Bourgeois, J.-P., Mechawar, N., Plomann, M., Salas, R., Schröder, H., Le Sourd, A.-M., Molles, B., Lindstrom, J., Gochberg-Sarver, A., Maskos, Uwe, Wevers, A., Maelicke, A.   +19 more
core   +1 more source

Alpha7 Nicotinic Acetylcholine Receptor Antagonists Prevent Meningitic Escherichia coli-Induced Blood-Brain Barrier Disruptions by Targeting the CISH/JAK2/STAT5b Axis. [PDF]

Biomedicines, 2022
Gong Z, Gao X, Li Y, Zou J, Lun J, Chen J, Zhou C, He X, Cao H.   +8 more
europepmc   +1 more source

The role of nicotinic acetylcholine receptors in lymphocyte development.

, 2006
International audienceThe sizes of lymphocyte populations in lymphoid organs of nicotinic acetylcholine receptor knockout and chimera (knockout/wild-type) mice were studied by flow cytometry.
Agenes, Fabien, Regis Grailhe, Marina Skok, Skok, Marina, Grailhe, Regis, Jean-Pierre Changeux, Changeux, Jean-Pierre, Fabien Agenes   +7 more
core   +1 more source

HIV, smoking, and the brain: a convergence of neurotoxicities

AIDS Research and Therapy
Purpose of review The purpose of this review is to characterize the combined effects of tobacco smoking and human immunodeficiency virus (HIV) infection in people with HIV (PWH) and identify possible therapeutic targets through shared mechanisms for ...
Benjamin L. Orlinick, Shelli F. Farhadian   +1 more
doaj   +1 more source

Cholinergic dysfunction-induced insufficient activation of alpha7 nicotinic acetylcholine receptor drives the development of rheumatoid arthritis through promoting protein citrullination via the SP3/PAD4 pathway. [PDF]

Acta Pharm Sin B, 2023
Lv C, Sun M, Guo Y, Xia W, Qiao S, Tao Y, Fang Y, Zhang Q, Zhu Y, Yalikun Y, Xia Y, Wei Z, Dai Y.   +12 more
europepmc   +1 more source

The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia

, 2002
Nicotinic acetylcholine receptors are members of the ligand-gated ion channel superfamily, that includes also gamma-amino-butiric-acid(A), glycine, and 5-hydroxytryptamine(3) receptors.
Charpantier, Eric, Dumont, Lionel, Tassonyi, Edomer, Bertrand, Daniel, Eric Charpantier, Muller, Dominique, Lionel Dumont, Daniel Bertrand, Edömer Tassonyi, Dominique Muller   +9 more
core   +1 more source