Results 101 to 110 of about 2,877 (196)
Neuroscience Letters, 1998 The rapid desensitization of alpha7 nicotinic acetylcholine receptors (nAChR) has presented a serious problem for the characterization of this receptor subtype, potentially confounding the interpretation of concentration-response relationships. However, the consistency of cell geometry and solution flow in oocyte recordings permits estimations of ...
Department of Pharmacology and Therapeutics, Box 100267 JHMHSC, University of Florida, Gainesville, FL 32610–0267, USA ( host institution ) +2 more
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Opportunities in precision psychiatry using PET neuroimaging in psychosis
Neurobiology of Disease, 2019 With the movement toward precision medicine in healthcare, recent studies of individuals with psychosis have begun to explore positron emission tomography (PET) as a tool to test for biochemical signatures that may distinguish subtypes of psychosis that ...
Jennifer M. Coughlin +2 more
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, 2014 Ionotropic GABA receptors are the targets for several classes of insecticides. One of the most widely-studied insect GABA receptors is RDL (resistance to dieldrin), originally isolated from Drosophila melanogaster.
Philip Biggin +11 more
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Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation.
, 2008 OBJECTIVES: Lung cancer is the most common cause of cancer death in the world. Cigarette smoking represents the major risk factor. Nicotine, an active component of cigarettes, can induce cell proliferation, angiogenesis and apoptosis resistance.
Cesario, Alfredo, Granone, Pierluigi
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, 2009 A novel class of alpha7 nicotinic acetylcholine receptor (nAChR) agonists has been discovered through high-throughput screening. The cis gamma-lactam scaffold has been optimized to reveal highly potent and selective alpha7 nAChR agonists with in vitro ...
Enz, Albert +7 more
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Journal of Pharmacological Sciences, 2010 .: This work investigated the expression of alpha-7 nicotinic acetylcholine receptor (α7nAChR) in the left ventricle and its putative role in cardiac angiogenesis in a pressure overload rat model induced by abdominal aorta coarctation. Blood pressure and
Min Ni +7 more
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Neural Regeneration Research, 2016 Glaucoma is a group of degenerative retinal diseases that damage the eye's optic nerve and can result in vision loss and blindness. It is characterized by optic neuropathy, cupping of the optic disk, and progressive loss of retinal ganglion cells (RGCs) and axons in the optic nerve.
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Frontiers in Immunology, 2017 Schizophrenia is one of the most debilitating mental disorders and is aggravated by the lack of efficacious treatment. Although its etiology is unclear, epidemiological studies indicate that infection and inflammation during development induces ...
Fabiana Maria das Graças Corsi-Zuelli +9 more
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, 2002 We examined the potential expression and function of alpha7 nicotinic acetylcholine receptors (nAChRs) in leukocytes. RT-PCR with alpha7 specific primers revealed the presence of the receptor mRNA in leukocytes.
Villiger, Y. +7 more
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, 2015 Recent evidence reveals a crucial role for acetylcholine and its receptors in the regulation of inflammation, particularly of nicotinic acetylcholine receptor alpha7 (Chrna7) and muscarinic acetylcholine receptor 3 (Chrm3).
Peters, Eva M. J. +7 more
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