Results 71 to 80 of about 2,375 (163)

The Spinal α7-Nicotinic Acetylcholine Receptor Contributes to the Maintenance of Cancer-Induced Bone Pain

Journal of Pain Research, 2021
Ting Yang1 1, Yaqun Zhou1 1, Wen Zhang1 1, Longqing Zhang1 1, Shuping Chen1 1, Chao Chen1 1, Feng Gao1 1, Hui Yang1 1, Anne Manyande2 2, Jie Wang3 3, Yuke Tian1 1, Xuebi Tian1 1 1Department of Anesthesiology, Tongji Hospital, Tongji Medical College ...
Yang T, Zhou Y, Zhang W, Zhang L, Chen S, Chen C, Gao F, Yang H, Manyande A, Wang J, Tian Y, Tian X   +11 more
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Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons. [PDF]

PLoS ONE, 2012
Kynurenic acid (KYNA), a classical ionotropic glutamate receptor antagonist is also purported to block the α7-subtype nicotinic acetylcholine receptor (α7* nAChR).
Peter Dobelis, Kevin J Staley, Donald C Cooper   +2 more
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Quantification of Proliferating and Mitotically Active Retinal Cells in Mice by Flow Cytometry

Bio-Protocol
Adult mammals lack the ability to regenerate retinal neurons after injury. However, in previous studies from this lab, topical application of the selective alpha7 nicotinic acetylcholine receptor (nAChR) agonist, PNU-282987, has been associated with an ...
Hope Vanzo-Sparks, Sarah Webster, Mark Webster, Cindy Linn   +3 more
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Novel Insights for Systemic Inflammation in Sepsis and Hemorrhage

Mediators of Inflammation, 2010
The inflammatory responses in sepsis and hemorrhage remain a major cause of death. Clinically, it is generally accepted that shock in sepsis or hemorrhage differs in its mechanisms.
Bolin Cai, Edwin A. Deitch, Luis Ulloa
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Cholinergic drugs inhibit in vitro megakaryopoiesis via the alpha7-nicotinic acetylcholine receptor

Platelets, 2011
Besides thrombopoietin several additional factors (i.e neurotransmitters and receptors) are known to be involved in the regulation of megakaryopoiesis at different stages. Recently, we identified functional α7 nicotinic acetylcholine receptors (nAChRα7) on platelets and megakaryocytic precursors. In platelets nAChRα7 form functional Ca(2+) channels and
Sophia, Thornton, Angelika, Schedel, Sabrina, Besenfelder, Harald, Klüter, Peter, Bugert   +4 more
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Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation

Journal of Neuroinflammation, 2010
Background A major site of initiation of inflammatory responses upon physical perturbation(s) and infection by invading organisms is the skin. Control of responses in this organ is, in part, modulated by the neuronal nicotinic acetylcholine receptor ...
Osborne Amber V, Gahring Lorise C, Reed Michelle, Rogers Scott W   +3 more
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α7 Nicotinic Acetylcholine Receptor Agonist PNU-282987 Ameliorates Cognitive Impairment Induced by Chronic Intermittent Hypoxia

Nature and Science of Sleep, 2021
Hui Shen, Yanling Meng, Dan Liu, Zheng Qin, Hong Huang, Lei Pan, Wei Wang, Jian Kang Institute of Respiratory Disease, The First Hospital of China Medical University, Shenyang, People’s Republic of ChinaCorrespondence: Wei WangInstitute of ...
Shen H, Meng Y, Liu D, Qin Z, Huang H, Pan L, Wang W, Kang J   +7 more
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The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation

Neurobiology of Disease, 2009
Stimulation of the nicotinic alpha7 acetylcholine receptor (nAChRα7) by nicotine or acetylcholine initiates the cholinergic anti-inflammatory pathway, a mechanism for neural inhibition of inflammation.
Eva-Maria Nicolussi, Sigismund Huck, Hans Lassmann, Monika Bradl   +3 more
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Comparative functional expression of nAChR subtypes in rodent DRG neurons

Frontiers in Cellular Neuroscience, 2013
We investigated the functional expression of nicotinic acetylcholine receptors (nAChRs) in heterogeneous populations of dissociated rat and mouse lumbar dorsal root ganglion (DRG) neurons by calcium imaging.
Nathan J. Smith, Arik J. Hone, Tosifa eMemon, Simon eBossi, Thomas E. Smith, J. Michael McIntosh, J. Michael McIntosh, J. Michael McIntosh, Baldomero M. Olivera, Russell W. Teichert   +9 more
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Dual Signaling Modes of Alpha7 Nicotinic Acetylcholine Receptors (α7 nAChRs)

Annals of Experimental and Molecular Biology, 2018
This themed section of the Annals of Experimental and Molecular Biology is the product of an article that is focusing on metabotropic signaling of an ionotropic channel alpha7 nicotinic ACh receptors (α7 nAChRs). The article talks about how α7 nAChR, being an ion channel, can function in a metabotropic-signaling mode via Gprotein coupling followed by ...
openaire   +1 more source