Results 41 to 50 of about 933,084 (308)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Alpha acids content in Czech hops from the 2023 harvest – forecasts, reality and trends

Kvasný průmysl
The most important weather factor for the hop growing season in 2023 was the rainy period in the last decade of July and the first decade of August, which replaced the previously warm and dry weather. Heavy rainfall with a total of 60–100 mm of water and
Karel Krofta, Alexandr Mikyška, Gabriela Fritschová, František Kroupa, Jana Tichá   +4 more
doaj   +1 more source

Ketonic bile acids in urine of infants during the neonatal period.

Journal of Lipid Research, 1989
Ketonic bile acids have been found to be quantitatively important in urine of healthy infants during the neonatal period. In order to determine their structures, the bile acids in urine from 11 healthy infants were analyzed by gas-liquid chromatography ...
E Wahlén, B Egestad, B Strandvik, J Sjoóvall   +3 more
doaj   +1 more source

Chirality in a quaternionic representation of the genetic code [PDF]

, 2015
A quaternionic representation of the genetic code, previously reported by the authors, is updated in order to incorporate chirality of nucleotide bases and amino acids.
Carlevaro, C. Manuel, Irastorza, Ramiro M., Vericat, Fernando   +2 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Altered bile acid metabolism in liver disease: concurrent occurrence of C-1 and C-6 hydroxylated bile acid metabolites and their preferential excretion into urine.

Journal of Lipid Research, 1990
C-1 and C-6 hydroxylated bile acid metabolites in various biological specimens from subjects with liver disease (cholestasis, liver cirrhosis, chronic hepatitis, acute hepatitis) were determined by gas-liquid chromatography-mass spectrometry.
J Shoda, N Tanaka, T Osuga, K Matsuura, H Miyazaki   +4 more
doaj   +1 more source

Free amino acids in a cave beetle \u3cem\u3eDarlingtonea kentuckensis\u3c/em\u3e Valentine (Coleoptera: Carabidae) [PDF]

, 1974
Free amino acids of Darlingtonea kentuckensis were investigated by two-dimensional, thin-layer chromatography on Silica Gel G. Thirteen amino acids which could be identifìed (alanine, glutamic acid, glycine, histidine, isoleucine and/or leucine, lysine ...
Sperka, R. J.
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Role of the Subunits Interactions in the Conformational Transitions in Adult Human Hemoglobin: an Explicit Solvent Molecular Dynamics Study

, 2012
Hemoglobin exhibits allosteric structural changes upon ligand binding due to the dynamic interactions between the ligand binding sites, the amino acids residues and some other solutes present under physiological conditions.
Baldwin J., Crespo A., Darden T., Essmann U., Fermi G., Gao J., Gelin B. R., Giovanni Bussi, Hess B., Hess B., Hoover W. G., Hornak V., Janin J., Jonathan O. Babalola, Jorgensen W. L., Kim K. W., Kovesi I., Laberge M., Lepeshkevich S. V., Lukin J. A., Mouawad L., Mouawad L., Mozzarelli A., Mozzarelli A., Olaniyi K. Yusuff, Parrinello M., Perutz M. F, Perutz M. F., Perutz M. F., Perutz M. F., Ramadas N., Rivetti C., Rodgers K. R., Safo M. K., Sahu S. C., Sahu S. C., Saito M., Shaanan B., Shibayama N., Silva M. M., Simone Raugei, Srinivasan R., Van der Spoel D., Xu Y., Yamada K.   +44 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source