Results 191 to 200 of about 3,275,969 (247)

Effects of Preventive Exposure to High Doses of Alpha-Lipoic Acid (ALA) on Testicular and Sperm Alterations Caused by Scrotal Heat Shock in Mice. [PDF]

open access: yesBiology (Basel)
Santos LC   +9 more
europepmc   +1 more source

Alpha lipoic acid for dementia

Cochrane Database of Systematic Reviews, 2002
Oxidative processes have been implicated in the pathogenesis of neurodegenerative dementias including Alzheimer's disease. Protecting the central nervous system against these damaging mechanisms may be a useful therapeutic approach. Alpha lipoic acid (ALA) is an endogenous antioxidant that interrupts cellular oxidative processes in both its oxidized ...
Anthony Klugman   +3 more
openaire   +2 more sources

Alpha lipoic acid intoxicatıon: An adult

The American Journal of Emergency Medicine, 2018
Alpha lipoic acid (ALA) is a potent antioxidant used to treat a variety of disorders. Although ALA is considered a very safe supplement and intoxication is very rare, acute high-dose ingestions can cause mortality. In this report, we discuss a very rare case of ALA intoxication to increase awareness of this issue.A 22-year-old female was referred to ...
FEREK EMİR, DUYGU   +2 more
openaire   +3 more sources

Alpha-lipoic acid prevents mitochondrial damage and neurotoxicity in experimental chemotherapy neuropathy

open access: yesExperimental Neurology, 2008
The study investigates if alpha-lipoic acid is neuroprotective against chemotherapy induced neurotoxicity, if mitochondrial damage plays a critical role in toxic neurodegenerative cascade, and if neuroprotective effects of alpha-lipoic acid depend on ...
Giuseppe Lauria   +2 more
exaly   +2 more sources

Alpha-lipoic acid as a biological antioxidant

Free Radical Biology and Medicine, 1995
alpha-Lipoic acid, which plays an essential role in mitochondrial dehydrogenase reactions, has recently gained considerable attention as an antioxidant. Lipoate, or its reduced form, dihydrolipoate, reacts with reactive oxygen species such as superoxide radicals, hydroxyl radicals, hypochlorous acid, peroxyl radicals, and singlet oxygen.
L, Packer, E H, Witt, H J, Tritschler
openaire   +2 more sources

Alpha-lipoic acid

Arbor Clinical Nutrition Updates, 2006
In a nutshellALA is a powerful antioxidant, both water and lipid soluble, that can also regenerate other antioxidants.A range of ‘antioxidant’ and other clinical indications (such as chelating toxic metals) have been tested in small, open trials and/or animal studies.
openaire   +1 more source

ALSUntangled #79: alpha-lipoic acid

Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
Alpha-lipoic acid (ALA) is a naturally occurring fatty acid. It serves as an essential cofactor for enzymatic reactions in mitochondrial energy production, is a potent antioxidant and has anti-inflammatory effects, which are plausible mechanisms in slowing ALS progression.
Alaina Giacobbe   +21 more
openaire   +2 more sources

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