In situ Alphavirus Assembly and Budding Mechanism Revealed by Cellular CryoET [PDF]
David Chmielewski +4 more
openalex +1 more source
Characterization of the Rubella Virus Nonstructural Protease Domain and Its Cleavage Site [PDF]
The region of the rubella virus nonstructural open reading frame that contains the papain-like cysteine protease domain and its cleavage site was expressed with a Sindbis virus vector. Cys-1151 has previously been shown to be required for the activity of
Chen, Jun-Ping +3 more
core
The mechanistic basis of protection by non-neutralizing anti-alphavirus antibodies
J. T. Earnest +5 more
semanticscholar +1 more source
U-CAN-seq: A Universal Competition Assay by Nanopore Sequencing
RNA viruses quickly evolve subtle genotypic changes that can have major impacts on viral fitness and host range, with potential consequences for human health.
Jennifer Diaz +10 more
doaj +1 more source
Semliki forest virus vectors engineered to express higher IL-12 levels induce efficient elimination of murine colon adenocarcinomas [PDF]
To evaluate the use of alphavirus vectors for tumor treatment we have constructed and compared two Semliki Forest virus (SFV) vectors expressing different levels of IL-12.
Prieto, J. (Jesús) +2 more
core
Imaging of the Alphavirus Capsid Protein during Virus Replication [PDF]
Yan Zheng, Margaret Kielian
openalex +1 more source
Regulation of Sindbis virus RNA replication: uncleaved P123 and nsP4 function in minus-strand RNA synthesis, whereas cleaved products from P123 are required for efficient plus-strand RNA synthesis [PDF]
Nonstructural proteins of Sindbis virus, nsPl, nsP2, nsP3, and nsP4, as well as intermediate polyproteins, are produced from two precursor polyproteins, Pl23 and Pl234, by a proteolytic enzyme encoded in the C-terminal half of nsP2.
Shirako, Yukio, Strauss, James H.
core +1 more source
Development and preclinical evaluation of an alphavirus replicon vaccine for influenza
Bolyn Hubby +16 more
openalex +1 more source

