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Alphaviruses are members of a group of small enveloped RNA viruses that includes important human pathogens such as Chikungunya virus and the equine encephalitis viruses.
Emily A. Byrd, Margaret Kielian
doaj +1 more source
The Poisson CUSUM Chart for Monitoring Small Counts: Addressing the Estimation Uncertainty
ABSTRACT This study addresses the impact of estimating in‐control parameters on the performance of the Poisson cumulative sum (CUSUM) chart in detecting an increase in the mean when the counts are small. To reduce false signals induced by estimation uncertainty, recommendations prescribe impractically large sample sizes or propose methods that widen ...
Stan Heidema +3 more
wiley +1 more source
Host nutritional status affects alphavirus virulence, transmission, and evolution.
Malnourishment, specifically overweight/obesity and undernourishment, affects more than 2.5 billion people worldwide, with the number affected ever-increasing. Concurrently, emerging viral diseases, particularly those that are mosquito-borne, have spread
James Weger-Lucarelli +10 more
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Chikungunya, an alphavirus infection presenting with fever, rash, and polyarthritis, is most often an acute febrile illness. Neurologic complications of chikungunya infection have been reported.
Licia Pacheco Pereira +7 more
doaj +1 more source
Mouse models of alphavirus-induced inflammatory disease [PDF]
Part of the Togaviridae family, alphaviruses are arthropod-borne viruses that are widely distributed throughout the globe. Alphaviruses are able to infect a variety of vertebrate hosts, but in humans, infection can result in extensive morbidity and ...
Taylor, Adam +9 more
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Viruses encode ion channel proteins called viroporins to assist in infection and immune evasion. The alphavirus 6K protein is classified as a member of the viroporin family of proteins.
Vashi Negi +2 more
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Ultrastructural morphogenesis of salmonid alphavirus 1 [PDF]
Studies on the ultrastructural morphogenesis of viruses give an insight into how the host cell mechanisms are utilized for new virion synthesis. A time course examining salmonid alphavirus 1 (SAV 1) assembly was performed by culturing the virus on ...
Adams, Alexandra +4 more
core +1 more source
Animal Models of Alphavirus-induced Inflammatory Disease [PDF]
Animal models that reflect key aspects of human disease are invaluable tools for understanding the mechanisms of disease pathogenesis and development of treatment strategies.
Taylor, Adam +11 more
core +1 more source
Chronic alphavirus infection of L cells.
Chronic infection of L cells with Sindbis virus, induced in the absence of antiviral antibody, was studied by virological methods in combination with light and electron microscopy. Both Sindbis virus and endogenous oncovirus antigens were revealed in the cells by immunofluorescence.
T A, Ivannikova +3 more
openaire +1 more source
Salmonid alphavirus infection causes skin dysbiosis in Atlantic salmon (Salmo salar L.) post-smolts. [PDF]
Interactions among host, microbiota and viral pathogens are complex and poorly understood. The goal of the present study is to assess the changes in the skin microbial community of Atlantic salmon (Salmo salar L.) in response to experimental infection ...
Lindsey J Moore +16 more
core +1 more source

