Results 151 to 160 of about 129,945 (312)

Purification and Characterization of an Neutral Proteinase Inhibitor from Bovine Neutrophils [PDF]

, 1987
Hintz, Petra, Jochum, Marianne, Mossmann, Horst   +2 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

JAK-Inhibitor Ruxolitinib als zukünftige neue Behandlungsoption? [PDF]

best practice onkologie, 2011
openaire   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

TRIM9 and TRIM26 Interact with UBQLN2^P497H to Modulate Its Proteasomal Degradation. [PDF]

ACS Chem Biol
Chen X, Cao Z, Liang X, Zhao T, Wang Y.
europepmc   +1 more source

Disturbances of selected plasma proteins in Hyperdynamic Septic Shock [PDF]

, 1982
A Ledgerwood, AO Aasen, AO Aasen, CB Laurell, D Collen, DL Heene, DM Rangel, EA Friedmann, EF Gersmeyer, FW Putnam, H Fritz, H Graeff, H Schiessler, H. Fritz, HG Lasch, J Johnson, J. Witte, JW Alexander, K Havemann, K Hochstrasser, K Messmer, K Ohlsson, K. Hochstrasser, M Jochum, M Jochum, M. Jochum, MS Losowsky, N Freudenberg, P Skansberg, PJ Hamilton, PM Starkey, R Dielt, R Egbring, R Hafter, R. Scherer, RG Lerner, W Schramm, W Schramm, W. Schramm   +38 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Lactate Dehydrogenase Inhibition Reverts the Fatty Acid-Induced Neurotoxic Phenotype of Astrocytes. [PDF]

Glia
Esteve D, Bresque M, Okhuevbie D, Ramachandran S, Pehar M, Vargas MR.   +5 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Prodrug strategies in developing antiviral nucleoside analogs. [PDF]

RSC Med Chem
Suresh RR, Abuduani T, Kasthuri M, Chen Z, Tber Z, Loubidi M, Zhang H, Zhou L, Zhou S, Li C, Kumari A, Tao S, Wiseman JM, Hurwitz SJ, Amblard F, Schinazi RF.   +15 more
europepmc   +1 more source