Results 71 to 80 of about 5,859 (181)

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

The Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts

Human Genomics, 2019
Background Mitochondrial DNA copy number (mtDNA CN) exhibits interindividual and intercellular variation, but few genome-wide association studies (GWAS) of directly assayed mtDNA CN exist.
Anna L. Guyatt, Rebecca R. Brennan, Kimberley Burrows, Philip A. I. Guthrie, Raimondo Ascione, Susan M. Ring, Tom R. Gaunt, Angela Pyle, Heather J. Cordell, Debbie A. Lawlor, Patrick F. Chinnery, Gavin Hudson, Santiago Rodriguez   +12 more
doaj   +1 more source

Distinct Temporal Stages of Infant Brain Processing Associate With Early Versus Later Autism Diagnosis

Developmental Science, Volume 29, Issue 5, September 2026.
ABSTRACT The expression of autism traits sufficient to meet criteria for a diagnosis can occur early (by 3 years) or later (from mid‐childhood onwards). It remains unknown whether variation in age of onset is due to clinical recognition or reflects distinct biological pathways.
Tessel Bazelmans, Tony Charman, Mark H. Johnson, Emily J. H. Jones, the BASIS Team   +4 more
wiley   +1 more source

Longitudinal Associations Between Pubertal Development and Youth Behavioral Adjustment in the Context of Parent and Peer Relationships

Social Development, Volume 35, Issue 3, August 2026.
ABSTRACT Puberty is a key developmental process influencing youths’ psychosocial adjustment, yet research has rarely examined its links to adaptive outcomes such as prosocial behavior. Using data from the Avon Longitudinal Study of Parents and Children, we applied linear mixed‐effects models to test associations between pubertal timing and tempo ...
Lia Ferschmann, Simone Dobbelaar, Christian Krog Tamnes, Stella Tsotsi, Yara Jo Toenders, Niamh MacSweeney   +5 more
wiley   +1 more source

Causal effects of reproductive traits on cognitive function: A two‐sample and multivariable mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 174, Issue 1, Page 424-435, July 2026.
Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, Volume 14, Issue 5, Page 1172-1182, July 2026.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Dietary Inflammatory Potential and Cardiometabolic Risk Factors in School‐Aged Adolescents

Pediatric Obesity, Volume 21, Issue 7, July 2026.
ABSTRACT Background The Dietary Inflammatory Index (DII) and its version adapted for children (C‐DII) have emerged as promising tools to estimate the inflammatory potential of the diet and to enhance the understanding of the relationship between subclinical chronic inflammation and cardiometabolic risk during adolescence.
Luana de Oliveira Leite, Mônica Leila Portela de Santana, Nadjane Ferreira Damascena, Jacqueline Costa Dias Pitangueira, Priscila Ribas de Farias Costa   +4 more
wiley   +1 more source

The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention‐deficit/hyperactivity disorder

The Journal of Physiology, Volume 604, Issue 14, Page 5711-5730, 15 July 2026.
Abstract figure legend Pregestational stress modifies germ‐cell epigenetic information, resulting in GABAergic dysfunction and E/I imbalance in the developing brain, thereby increasing susceptibility to ASD‐and ADHD‐related neurodevelopmental abnormalities in offspring.
Samaneh Ahmadian‐Moghadam, Ehsan Saboory, Shiva Roshan‐Milani   +2 more
wiley   +1 more source

Measuring religiosity in longitudinal secondary datasets: Comparison of single-item measures with validated scales in a UK cohort study (ALSPAC) [version 2; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research
Background Many studies use single-item variables to measure religiosity, such as religious belief, identity or service attendance. However, there are many different hypothesised dimensions of religiosity and it is often unclear how these single-item ...
Kate Northstone, Jean Golding, Jimmy Morgan, Isaac Halstead, Daniel Major-Smith   +4 more
doaj   +1 more source

Does early introduction of solid feeding lead to early cessation of breastfeeding?

Maternal and Child Nutrition, 2020
Mixed milk feeding increases the likelihood of breastfeeding cessation, but it is not known if solid feeding (SF) has the same effect. We have identified 10,407 infants breastfed for at least 8–10 weeks from three large U.K.
Angelina Lessa, Ada L. Garcia, Pauline Emmett, Sarah Crozier, Sian Robinson, Keith M. Godfrey, Charlotte M. Wright   +6 more
doaj   +1 more source