Results 51 to 60 of about 28,483 (297)

No space Left for Intravenous thrombolysis in acute stroke [PDF]

open access: yes, 2016
Recent successful clinical trials of endovascular thrombectomy for large artery ischaemic stroke have established the value of this treatment modality as an adjunct to intravenous thrombolysis, not as an alternative: thrombectomy delivery was undertaken ...
Muir, Keith
core   +1 more source

Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset [PDF]

open access: yes, 2010
<p><b>Background and Purpose:</b> Antiplatelets (APs) may increase the risk of symptomatic intracerebral hemorrhage (ICH) following intravenous thrombolysis after ischemic stroke.</p> <p><b>Methods:</b> We ...
Ahmed, N.   +10 more
core   +8 more sources

Effectiveness of Standard-Dose vs. Low-Dose Alteplase for Acute Ischemic Stroke Within 3–4.5 h

open access: yesFrontiers in Neurology, 2022
BackgroundThe efficacy and safety of intravenous alteplase administered 3–4.5 h after acute ischemic stroke have been demonstrated. However, whether responses differ between low-dose and standard-dose alteplase during this time window and whether certain
Chih-Hao Chen   +18 more
doaj   +1 more source

Efficacy and safety of catheter-directed thrombolytic therapy of alteplase and urokinase for the treatment of deep vein thrombosis: a Meta-analysis [PDF]

open access: yesYixue xinzhi zazhi, 2023
Objective To systematically review the effectiveness and safety of cathe-ter-directed thrombolytic therapy (CDT) using alteplase and urokinase in the treatment of deep vein thrombosis (DVT) in the lower extremities.Method PubMed, The Cochrane Library ...
Hong-Yan LI   +6 more
doaj   +1 more source

Transthoracic Drainage of an Intrapulmonary Bronchogenic Cyst With an Intercostal Catheter [PDF]

open access: yesRespirol Case Rep
We present the case of an 84‐year‐old female with a large intrapulmonary bronchogenic cyst who presented with progressive dyspnoea, haemoptysis, and fevers. Due to relative contraindications for surgery, an ultrasound‐guided percutaneous intercostal catheter insertion with administration of fibrinolytic and mucolytic therapy was performed to evacuate ...
Hoang K, Brown M, Nguyen P, Badiei A.
europepmc   +2 more sources

Statistical analysis of the primary outcome in acute stroke trials [PDF]

open access: yes, 2012
Common outcome scales in acute stroke trials are ordered categorical or pseudocontinuous in structure but most have been analyzed as binary measures. The use of fixed dichotomous analysis of ordered categorical outcomes after stroke (such as the modified
Altman, H.   +7 more
core   +1 more source

Does hemispheric lateralization influence functional and cardiovascular outcomes after stroke?: an analysis of placebo-treated patients from prospective acute stroke trials [PDF]

open access: yes, 2008
<p><b>Background and Purpose:</b> The influence of stroke lateralization on functional and cardiovascular outcome after stroke is not well established.
Fink, J.N.   +3 more
core   +1 more source

Thrombolysis is associated with consistent functional improvement across baseline stroke severity: a comparison of outcomes in patients from the Virtual International Stroke Trials Archive (VISTA) [PDF]

open access: yes, 2010
<p><b>Background and Purpose:</b> Baseline stroke severity predicts outcomes among thrombolysed patients. The baseline National Institutes of Health Stroke Scale (NIHSS) thresholds are sometimes used to select patients for thrombolysis,
Grotta, J.C.   +3 more
core   +1 more source

Tenecteplase vs. Alteplase for Intravenous Thrombolytic Therapy of Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

open access: yesNeurological Therapeutics, 2023
In recent years, there has been controversy surrounding the use of tenecteplase, a drug for treating acute ischemic stroke (AIS). To help doctors make better decisions, we compared the safety and effectiveness of tenecteplase with another drug called ...
Ziyi Shen   +6 more
semanticscholar   +1 more source

The SITS-UTMOST: a registry-based prospective study in Europe investigating the impact of regulatory approval of intravenous Actilyse in the extended time window (3–4.5 h) in acute ischaemic stroke [PDF]

open access: yes, 2016
Introduction: The SITS-UTMOST (Safe Implementation of Thrombolysis in Upper Time window Monitoring Study) was a registry-based prospective study of intravenous alteplase used in the extended time window (3–4.5 h) in acute ischaemic stroke to evaluate ...
Ahmed, Niaz   +11 more
core   +1 more source

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