Results 111 to 120 of about 331,356 (244)

Targeting the Alternative Complement Pathway With Iptacopan to Treat IgA Nephropathy: Design and Rationale of the APPLAUSE-IgAN Study. [PDF]

Kidney Int Rep, 2023
Rizk DV, Rovin BH, Zhang H, Kashihara N, Maes B, Trimarchi H, Perkovic V, Meier M, Kollins D, Papachristofi O, Charney A, Barratt J.   +11 more
europepmc   +1 more source

Severe COVID-19 is associated with hyperactivation of the alternative complement pathway. [PDF]

J Allergy Clin Immunol, 2022
Boussier J, Yatim N, Marchal A, Hadjadj J, Charbit B, El Sissy C, Carlier N, Pène F, Mouthon L, Tharaux PL, Bergeron A, Smadja DM, Rieux-Laucat F, Duffy D, Kernéis S, Frémeaux-Bacchi V, Terrier B.   +16 more
europepmc   +1 more source

Therapeutic targeting of alternative pathway and C5 but not C5a protects from disease development in a preclinical model of autoimmune blistering dermatosis

Frontiers in Immunology
IntroductionEpidermolysis Bullosa Acquisita (EBA) is an autoimmune blistering dermatosis characterized by autoantibodies (AAbs) against type VII collagen (COL7) located at the dermal epidermal junction (DEJ).
Björn Laffer, Mareike Ohms, Samyr Kenno, Ping Tsui, Elvira Ehlers-Jeske, Wenru Song, Wen-Chao Song, Jörg Köhl   +7 more
doaj   +1 more source

Alternative Complement Pathway Inhibition With Iptacopan for the Treatment of C3 Glomerulopathy-Study Design of the APPEAR-C3G Trial. [PDF]

Kidney Int Rep, 2022
Bomback AS, Kavanagh D, Vivarelli M, Meier M, Wang Y, Webb NJA, Trapani AJ, Smith RJH.   +7 more
europepmc   +1 more source

Activation of the Alternative Pathway of Guinea Pig Complement by Sendai Virus‐Treated Cells [PDF]

, 1979
Noriko Okada, Hiroshi Shibuta, Hidechika Okada   +2 more
openalex   +1 more source

Complement Pathway Associated Glomerulopathies [PDF]

European Medical Journal, 2016
The complement system causes kidney injury in a variety of different diseases, and clinical evaluation of the complement system is an important part of the diagnostic workup of patients with glomerulonephritis.
Yasar Caliskan
doaj  

The Capacity of Lymphoblastoid Cells to Activate the Alternative Complement Pathway Is Correlated with their Transformation by Epstein-Barr Virus [PDF]

, 1978
I. McConnell, P. J. Lachmann, Thomas F. Lint, George Klein   +3 more
openalex   +1 more source

Adipsin of the Alternative Complement Pathway Is a Potential Predictor for Preeclampsia in Early Pregnancy. [PDF]

Front Immunol, 2021
Liu M, Luo X, Xu Q, Yu H, Gao L, Zhou R, Wang T.   +6 more
europepmc   +1 more source

Requirements of immunoglobulin and the classical and alternative complement pathways for phagocytosis and intracellular killing of multiple strains of Gram-negative aerobic bacilli [PDF]

, 1979
P Leist-Welsh, A. B. Bjornson
openalex   +1 more source

Complement Activation in Semisolid Media: Insolubilization of Alternative Pathway Convertases in Agar Gels with C3 Nephritic Factor-Containing Sera [PDF]

, 1977
Mohammed A. Arnaout, Alvin E. Davis, Fred S. Rosen, Chester A. Alper   +3 more
openalex   +1 more source