Results 101 to 110 of about 135,678 (188)

3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase

, 2009
6 pages, 4 figures.-- Supporting information (SI materials and methods, 6 pages) available at: http://www.pnas.org/content/suppl/2009/01/09/0810860106.DCSupplemental/0810860106SI.pdfGeneration of the alternative pathway C3-convertase, the central ...
Llorca, Óscar, Rodríguez de Córdoba, Santiago, Tortajada, Agustín, Montes, Tamara, Tortajada Alonso, Agustín, Torreira, Eva   +5 more
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Adipsin of the Alternative Complement Pathway Is a Potential Predictor for Preeclampsia in Early Pregnancy. [PDF]

Front Immunol, 2021
Liu M, Luo X, Xu Q, Yu H, Gao L, Zhou R, Wang T.   +6 more
europepmc   +1 more source

Complement alternative pathway acts as a positive feedback amplification of neutrophil activation

, 2011
Complement alternative pathway plays an important, but not clearly understood, role in neutrophil-mediated diseases. We here show that neutrophils themselves activate complement when stimulated by cytokines or coagulation-derived factors. In whole blood,
Laurent Camous, Soumeya Brachemi, Lubka Roumenina, Sylvain Bigot, Philippe Lesavre, Lise Halbwachs-Mecarelli, Véronique Frémeaux-Bacchi   +6 more
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Alternative pathway-mediated tubular complement activation in human proteinuric kidney diseases:a proof-of-concept study [PDF]

BACKGROUND: Proteinuria, irrespective of the primary disease, may cause progressive kidney injury by several mechanisms, including tubular complement activation. Experimental studies have shown that complement activation at the apical side of the tubules
Bajema, Ingeborg M, Berger, Stefan P, van den Born, Jacob, Daha, Mohamed R, Alkaff, Firas F; id_orcid, Tiller, Gesa; id_orcid, Lammerts, Rosa G M; id_orcid, van den Heuvel, Marius C   +7 more
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Alternative Complement Pathway Inhibition Does Not Abrogate Meningococcal Killing by Serum of Vaccinated Individuals. [PDF]

Front Immunol, 2021
Ispasanie E, Muri L, Schubart A, Thorburn C, Zamurovic N, Holbro T, Kammüller M, Pluschke G.   +7 more
europepmc   +1 more source

Prevention of intrauterine fetal growth restriction by administrating C1q/TNF-related protein 6, a specific inhibitor of the alternative complement pathway. [PDF]

J Assist Reprod Genet, 2022
Kurokawa M, Takeshita A, Hashimoto S, Koyama M, Morimoto Y, Tachibana D.   +5 more
europepmc   +1 more source

COVID-19 microthrombosis: unusually large VWF multimers are a platform for activation of the alternative complement pathway under cytokine storm. [PDF]

Int J Hematol, 2022
Fujimura Y, Holland LZ.
europepmc   +1 more source

Alternative Complement Pathway Is Activated and Associated with Galactose-Deficient IgA₁ Antibody in IgA Nephropathy Patients. [PDF]

Front Immunol, 2021
Chiu YL, Lin WC, Shu KH, Fang YW, Chang FC, Chou YH, Wu CF, Chiang WC, Lin SL, Chen YM, Wu MS.   +10 more
europepmc   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab. [PDF]

Ann Clin Transl Neurol
Gerischer L, Stascheit F, Mönch M, Doksani P, Dusemund C, Herdick M, Mergenthaler P, Stein M, Suboh A, Schröder-Braunstein J, Wabnitz G, Lünemann JD, Lehnerer S, Hoffmann S, Meisel A.   +14 more
europepmc   +1 more source

The complement factsbook /

, 2000
The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins.
Morley, Bernard J., Walport, Mark.
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