Results 131 to 140 of about 433,637 (362)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Hipocomplementemia en pacientes con enfermedad de Hodgkin Hypocomplementaemia in patients with Hodgkin disease

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2003
The haemolytic activity of the classical and alternative pathways, of factors B and D, as well as of the levels of C1q, C3 and C4 was determined in the serum of 24 adult patients with Hodgkin disease at different clinical stages.
doaj  

Exploring the involvement of the alternative complement pathway in non-infectious uveitis pathogenesis. [PDF]

Front Immunol, 2023
Kulshrestha P, Goel P, Murthy S, Tyagi M, Basu S, Gogri P, Kaur I.   +6 more
europepmc   +1 more source

Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis. [PDF]

, 2016
Cholesterol crystals (CC) play an essential role in the formation of atherosclerotic plaques. CC activate the classical and the alternative complement pathways, but the role of the lectin pathway is unknown.
Genster, Ninette, Gál, Péter, Pilely, Katrine, Pál, Gábor, Rosbjerg, Anne   +4 more
core   +1 more source

Alternative Complement Pathway Induction by ANCA [PDF]

The American Journal of Pathology, 2008
This Correspondence relates to "Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies" (Am J Pathol 2007, 170:52–64).
openaire   +2 more sources

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Low-molecular weight inhibitors of the alternative complement pathway. [PDF]

Immunol Rev, 2023
Schubart A, Flohr S, Junt T, Eder J.
europepmc   +1 more source

Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition

, 2017
Introduction IgA nephropathy (IgAN) is characterized by glomerular deposition of galactose-deficient IgA1 and complement proteins and leads to renal impairment.
Constantinou, N, Cook, HT, Hansen, AG, Lomax-Browne, HJ, Medjeral-Thomas, NR, Pickering, MC, Pusey, CD, Thiel, S, Troldborg, A, Willicombe, M   +9 more
core   +2 more sources

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Activation of the Alternative Pathway of Guinea Pig Complement by Sendai Virus‐Treated Cells [PDF]

, 1979
Noriko Okada, Hiroshi Shibuta, Hidechika Okada   +2 more
openalex   +1 more source