Activation of the Alternative Pathway of Guinea Pig Complement by Sendai Virus‐Treated Cells [PDF]
, 1979 Noriko Okada +2 more
openalex +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source
Alterations in the complement cascade in post-traumatic stress disorder
Allergy, Asthma & Clinical Immunology, 2010 Background In the present study we assessed the functional state of the major mediator of the immune response, the complement system, in post-traumatic stress disorder (PTSD).
Hovhannisyan Lilit P +3 more
doaj +1 more source
Components of the alternative complement pathway in patients with psoriasis
Acta Dermatovenerologica Alpina Pannonica et Adriatica, 2017 Psoriasis is a chronic inflammatory skin disease. Adipose tissue plays important roles in the events that regulate body metabolism. This study determined the levels of complement 3 ( C3), acylation-stimulating protein (ASP), and adipsin, which take part in the alternate complement pathway, and are synthesized in and secreted by adipose tissue.Thirty ...
Betül Şereflican, Guler Bugdayci
openaire +3 more sources
FEBS Open Bio, EarlyView.The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley +1 more source
Functional evaluation of rare variants in complement factor I using a minigene assay
Frontiers in ImmunologyThe regulatory serine protease, complement factor I (FI), in conjunction with one of its cofactors (FH, C4BP, MCP, or CR1), plays an essential role in controlling complement activity through inactivation of C3b and C4b.
Cobey J. H. Donelson +4 more
doaj +1 more source
Qihuang Granule protects the retinal pigment epithelium from oxidative stress via regulation of the alternative complement pathway. [PDF]
BMC Complement Med Ther, 2023 Wang Y +6 more
europepmc +1 more source
Activation of the alternative complement pathway with rabbit erythrocytes by circumvention of the regulatory action of endogenous control proteins [PDF]
, 1977 D T Fearon, K. Frank Austen
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement [PDF]
, 2004 The complement system is important in immunosurveillance against tumors. However, malignant cells are usually resistant to complement-mediated lysis. In this study, we examine the expression of factor H, an inhibitor of complement activation, and factor ...
Ajona, D. (Daniel) +8 more
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