Finding Thermodynamically Favorable Pathways in Reaction Networks using Flows in Hypergraphs and Mixed Integer Linear Programming [PDF]
arXivFinding pathways that optimize the formation of a particular target molecule in a chemical reaction network is a key problem in many settings, including reactor systems. Reaction networks are mathematically well represented as hypergraphs, a modeling that facilitates the search for pathways by computational means.
arxiv
The eBDIMS path-sampling server: generation, classification and interactive visualization of protein ensembles and transition pathways in 2D-motion space [PDF]
arXiv, 2018 The recent rise of cryo-EM and X-ray high-throughput techniques is providing a wealth of new structures trapped in different conformations. Understanding how proteins transition between different conformers, and how they relate to each other in terms of function is not straightforward, and highly depends on the choice of the right set of degrees of ...
arxiv
Alternative pathway of complement: demonstration and characterization of initiating factor and its properdin-independent function. [PDF]
, 1976 Robert D. Schreiber +2 more
openalex +1 more source
Arthritis Care &Research, EarlyView.Objective Promoting Resilience in Stress Management (PRISM) is a resilience coaching program designed for adolescents with chronic illness. We aimed to examine the perceived feasibility, acceptability, and appropriateness of PRISM among pediatric rheumatologists treating adolescents with chronic musculoskeletal pain and obtain recommendations for ...
Sabrina Gmuca +9 more
wiley +1 more source
Complement Pathway Associated Glomerulopathies [PDF]
European Medical Journal, 2016 The complement system causes kidney injury in a variety of different diseases, and clinical evaluation of the complement system is an important part of the diagnostic workup of patients with glomerulonephritis.
Yasar Caliskan
doaj
Alternative Pathway of Complement Activation in Full Term and Premature Infants [PDF]
, 1979 Robert C. Strunk +2 more
openalex +1 more source
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source
Advanced Biology, EarlyView.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
Adipsin of the Alternative Complement Pathway Is a Potential Predictor for Preeclampsia in Early Pregnancy. [PDF]
Front Immunol, 2021 Liu M +6 more
europepmc +1 more source
A Morphotropic Phase Boundary in MA$_{1-x}$FA$_x$PbI$_3$: Linking Structure, Dynamics, and Electronic Properties [PDF]
arXivUnderstanding the phase behavior of mixed-cation halide perovskites is critical for optimizing their structural stability and optoelectronic performance. Here, we map the phase diagram of MA$_{1-x}$FA$_x$PbI$_3$ using a machine-learned interatomic potential in molecular dynamics simulations.
arxiv