Chemotaxigenesis and activation of the alternative complement pathway by encapsulated and non-encapsulated Cryptococcus neoformans [PDF]
K A Laxalt, Thomas R. Kozel
openalex +1 more source
Components of the alternative complement pathway in patients with psoriasis
Psoriasis is a chronic inflammatory skin disease. Adipose tissue plays important roles in the events that regulate body metabolism. This study determined the levels of complement 3 ( C3), acylation-stimulating protein (ASP), and adipsin, which take part in the alternate complement pathway, and are synthesized in and secreted by adipose tissue.Thirty ...
Betül Şereflican, Guler Bugdayci
openaire +3 more sources
Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan+8 more
wiley +1 more source
Targeting the Alternative Complement Pathway With Iptacopan to Treat IgA Nephropathy: Design and Rationale of the APPLAUSE-IgAN Study. [PDF]
Rizk DV+11 more
europepmc +1 more source
The dynamics of alternative pathways to compensatory substitution [PDF]
The role of epistatic interactions among loci is a central question in evolutionary biology and is increasingly relevant in the genomic age. While the population genetics of compensatory substitution have received considerable attention, most studies have focused on the case when natural selection is very strong against deleterious intermediates.
arxiv
Alternative pathway of complement: demonstration and characterization of initiating factor and its properdin-independent function. [PDF]
Robert D. Schreiber+2 more
openalex +1 more source
Objective Promoting Resilience in Stress Management (PRISM) is a resilience coaching program designed for adolescents with chronic illness. We aimed to examine the perceived feasibility, acceptability, and appropriateness of PRISM among pediatric rheumatologists treating adolescents with chronic musculoskeletal pain and obtain recommendations for ...
Sabrina Gmuca+9 more
wiley +1 more source
Severe COVID-19 is associated with hyperactivation of the alternative complement pathway. [PDF]
Boussier J+16 more
europepmc +1 more source
Finding Thermodynamically Favorable Pathways in Reaction Networks using Flows in Hypergraphs and Mixed Integer Linear Programming [PDF]
Finding pathways that optimize the formation of a particular target molecule in a chemical reaction network is a key problem in many settings, including reactor systems. Reaction networks are mathematically well represented as hypergraphs, a modeling that facilitates the search for pathways by computational means.
arxiv
Alternative Pathway of Complement Activation in Full Term and Premature Infants [PDF]
Robert C. Strunk+2 more
openalex +1 more source