Results 181 to 190 of about 343,845 (337)

The complement alternative pathway in health and disease—activation or amplification? [PDF]

, 2022
R. A. Harrison, Claire L. Harris, Joshua M. Thurman   +2 more
openalex   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

Alternative Pathway Activation of the Complement System in Preterm Infants with Early Onset Infection [PDF]

, 1997
E. P. Zilow, W. Hauck, O Linderkamp, G. Zilow   +3 more
openalex   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

International Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Human Factor D of the Alternative Complement Pathway: Purification and Characterization [PDF]

, 1977
John E. Volanakis, Ralph E. Schrohenloher, Robert M. Stroud   +2 more
openalex   +1 more source

Image_2_The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure.tiff

, 2021
Margrethe Flesvig Holt (11874794), Annika E. Michelsen (6834731), Negar Shahini (11874797), Elisabeth Bjørkelund (9250596), Christina Holt Bendz (11874800), Richard J. Massey (10167614), Camilla Schjalm (750154), Bente Halvorsen (151367), Kaspar Broch (527245), Thor Ueland (307058), Lars Gullestad (224437), Per H. Nilsson (10788369), Pål Aukrust (151370), Tom Eirik Mollnes (7470011), Mieke C. Louwe (6983585)   +14 more
openalex   +2 more sources

Geometric Optimization and Mechanical Performance Enhancement of Auxetic Structures for High‐Impact Applications Through Fused Deposition Modeling

Advanced Engineering Materials, EarlyView.
This study explores the mechanical performance of three auxetic structures, identifying a re‐entrant‐star hybrid as the most effective for impact absorption. Finite element simulations and experiments demonstrate significant gains in energy absorption and flexural strength after geometric optimization. This study investigates the mechanical performance
Malik Hassan, Manjusri Misra, Alexander Bardelcik, Stefano Gregori, Amar K. Mohanty   +4 more
wiley   +1 more source

Activation of the alternative complement pathway and its relevance for sodium retention in experimental nephrotic syndrome. [PDF]

Pflugers Arch
Essigke D, Kalo MZ, Kong L, Wörn M, Saad MK, Omage K, Bohnert BN, Birkenfeld AL, Atkinson JP, Wu X, Artunc F.   +10 more
europepmc   +1 more source

Alternative Complement Pathway Activation Provokes a Hypercoagulable State with Diminished Fibrinolysis. [PDF]

Shock, 2020
Samuels JM, Coleman JR, Moore EE, Bartley M, Vigneshwar N, Cohen M, Silliman CC, Sauaia A, Banerjee A.   +8 more
europepmc   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source