Results 181 to 190 of about 433,637 (362)

Eculizumab in atypical hemolytic uremic syndrome: long-term clinical course and histological findings [PDF]

, 2018
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy associated with defective regulation of the alternative complement pathway.
Bucher, Barbara, Gugger, Mathias, Riedl, Magdalena, Simonetti, Giacomo, Tschumi, Sibylle   +4 more
core  

Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials

Advanced Engineering Materials, EarlyView.
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani, Surabhi Nadigotti, Erfan Fatehi, Derek Aranguren van Egmond, Behnam Ashrafi   +4 more
wiley   +1 more source

Inhibiting the alternative pathway of complement by reducing systemic complement factor B: Randomized, double-blind, placebo-controlled phase 1 studies with Sefaxersen

Immunobiology
An over-active alternative complement pathway has been implicated in the pathophysiology of multiple diseases, including IgA nephropathy and geographic atrophy secondary to age related macular degeneration.
Michael L. McCaleb, Steven G. Hughes, Tamar R. Grossman, Ashley Frazer-Abel, Bill Jung, Lixuan Yin, Scott P. Henry, Brett P. Monia, Eugene Schneider, Richard Geary, Gary T. Brice   +10 more
doaj  

Alternative Complement Pathway Inhibition Does Not Abrogate Meningococcal Killing by Serum of Vaccinated Individuals. [PDF]

Front Immunol, 2021
Ispasanie E, Muri L, Schubart A, Thorburn C, Zamurovic N, Holbro T, Kammüller M, Pluschke G.   +7 more
europepmc   +1 more source

ALTERNATIVE COMPLEMENT PATHWAY (AP) IN CHILDREN WITH NEPHROSIS (CN) [PDF]

, 1977
Michael E. Norman, Arlene Taylor, Ulf Nilsson, Mary Ann South   +3 more
openalex   +1 more source

Method, liposome collection, and kit for determining complement activity [PDF]

The present invention relates to a method of determining complement activity, wherein said method comprises determining classical complement pathway activity, determining alternative complement pathway activity, and/or determining lectin complement ...
Baumner, Antje, Pauly, Diana, Poppelaars, Felix, Spitzenberg, Clemens   +3 more
core  

Recent Progress on 2D‐Material‐Based Smart Textiles: Materials, Methods, and Multifunctionality

Advanced Engineering Materials, EarlyView.
Advancements in 2D‐material‐integrated smart textiles are reviewed, with a focus on materials, fabrication methods, and multifunctional applications, including energy harvesting, monitoring, EMI shielding, energy storage, and thermal management. The discussion addresses key challenges and provides insights into the future development of next‐generation
Yong Choi, Jiheon Kim, Jaemin Lee, Xinqi Chen, Byungseok Seo, Wonjoon Choi   +5 more
wiley   +1 more source

COVID-19 microthrombosis: unusually large VWF multimers are a platform for activation of the alternative complement pathway under cytokine storm. [PDF]

Int J Hematol, 2022
Fujimura Y, Holland LZ.
europepmc   +1 more source

NetAurHPD: Network Auralization Hyperlink Prediction Model to Identify Metabolic Pathways from Metabolomics Data [PDF]

arXiv
Metabolite biosynthesis is regulated via metabolic pathways, which can be activated and deactivated within organisms. Understanding and identifying an organism's metabolic pathway network is a crucial aspect for various research fields, including crop and life stock breeding, pharmacology, and medicine.
arxiv  

The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase [PDF]

, 1986
Michael K. Pangburn, Hans J. Müller‐Eberhard   +1 more
openalex   +1 more source