Results 271 to 280 of about 539,466 (329)

Alternative pathway of complement in multiple myeloma

American Journal of Hematology, 1981
AbstractThe alternative pathway of complement was studied in 16 newly diagnosed and 2 previously treated patients with multiple myeloma. Functional activity of this pathway was abnormal in 10 of these 18 patients (55%). These abnormalities correlated with depressed levels of alternative pathway components in 3 of 10 patients, but in the remaining 7, no
E H, Kraut, A L, Sagone
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[Alternative complement pathway].

La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984
The alternative complement pathway comprises three component proteins C3, B, D and three regulatory proteins P, H and I. These plasma proteins represent the major humoral defense mechanism against infection in a non-immune host. The following topics are reviewed: biochemistry of the alternative pathway proteins; molecular mechanisms of activation and ...
M H, Jouvin, M, Kazatchkine
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The Alternative Pathway of Complement Activation

1976
Publisher Summary This chapter presents the alternative pathway of complement activation. Two pathways for the recruitment of complement and its biological activities exist in plasma and serum. The first is termed as the “classical pathway,” which is triggered by contact of C1 with immune complexes containing antibodies of the immunoglobulin G (IgG ...
O, Götze, H J, Müller-Eberhard
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Trichomonas vaginalis: alternative pathway activation of complement

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1982
Serum from adult human donors lysed Trichomonas vaginalis. The lytic effect was eliminated by heat-inactivation of serum (56 degrees C, 30 min). No serum donor exhibited significantly increased antibody against the parasite as measured by indirect immunofluorescence. Treatment of serum with ethylene glycol-bis (B-aminoethyl ether)-N, N-tetraacetic acid
T W, Holbrook, R J, Boackle, J, Vesely, B W, Parker   +3 more
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Gangliosides can activate human alternative complement pathway

International Immunology, 1993
The alternative complement pathway (ACP) in vertebrates is known to be important in inflammatory reactions, and to be activated by foreign substances such as bacterial lipopolysaccharide (LPS) and zymosan, although to date no intrinsic activators have been identified except complement receptor type 2.
H, Oshima, G, Soma, D, Mizuno
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[The alternative complement pathway].

Pathologie-biologie, 1984
The alternative complement pathway comprises three component proteins C3, B, D and three regulatory proteins P, H and I. These plasma proteins represent the major humoral defense mechanism against infection in a non-immune host. The following topics are reviewed: biochemistry of the alternative pathway proteins; molecular mechanisms of activation and ...
M H, Jouvin, M, Kazatchkine
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Alternative complement pathway: Activity levels in allogeneic pregnancy

Experientia, 1976
Classical and alternative complement pathway activities have been evaluated in sera of women in progressive stages of gestation and in pregnant mice belonging to outbred or inbred matings, as compared to suitable controls. While classical C pathway was found to be unmodified, the alternative one attained in pregnancy significantly higher activity ...
M, Brai, G, Tolone, A, Magro, H, Waks, M, Brai   +4 more
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[Alternative complement pathway (author's transl)].

La Nouvelle presse medicale, 1979
The dual role of the alternative complement pathway in recognition of foreign substances by a non-immune host and in the intrinsic regulation of the complement sequence is now well recognized. Activation of this pathway occurs through escape from its regulatory mechanisms induced by the activating principle; its functional expression depends on the ...
M, Kazatchkine, U, Nydegger, D T, Fearon
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Restriction of alternative complement pathway activation by sialosylglycolipids

Nature, 1982
Although sheep erythrocytes do not activate the alternative complement pathway (ACP) of human serum, the erythrocytes gain a capacity to activate human ACP following removal of membrane sialic acid by neuraminidase treatment1–3. Therefore, asialoglycoconjugates generated from sialosylglycoconjugates by neuraminidase treatment might be responsible for ...
N, Okada, T, Yasuda, H, Okada
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Complement Fixation by Aggregated IgE through Alternate Pathway

The Journal of Immunology, 1972
Summary Nonspecifically aggregated E myeloma protein fixed late component(s) of guinea pig and human C. Evidence was presented that the C fixation by the aggregate probably goes through an alternate pathway. Comparisons among aggregated Fc, aggregated F(ab′)2 and aggregated IgE with respect to the C-fixing activity showed that aggregated
T, Ishizaka, C M, Sian, K, Ishizaka
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