Results 81 to 90 of about 161,686 (253)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Rekayasa Algoritma Gravity Location Models Untuk Penentuan Lokasi Lumbung Pangan Masyarakat Kabupaten Minahasa Tenggara

JuTISI (Jurnal Teknik Informatika dan Sistem Informasi), 2015
Focus of central government program in order to sustain tenacity of food is to align charging of barns of food society. This paper would examine the Gravity Location Model algorithm which is part of the network development strategy of supply chain ...
Aldian Umbu Tamu Ama, Eko Sediyono, Adi Setiawan   +2 more
doaj   +1 more source

"La misma realidad de cada lugar es diferente" ("The same reality of each place is different"): A Case Study of an Organic Farmers Market in Lima, Peru

Journal of Agriculture, Food Systems, and Community Development, 2016
Studies of alternative food networks have proliferated in Europe and North America while relatively little attention has been paid to similar networks in the global South.
Kevin Cody
doaj   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Immunosuppressive Drug Use in Limited Systemic Sclerosis: An International Survey

Arthritis Care &Research, EarlyView.
Objective Current guidelines recommend immunosuppressive treatment for diffuse cutaneous systemic sclerosis but are less clear on their use in limited cutaneous systemic sclerosis (lcSSc) in the absence of internal organ complications. We conducted an international survey to understand current immunosuppressive drug prescribing patterns in lcSSc ...
Sabrina Hoa, Yicheng Mu, Marie Hudson, Janet Pope   +3 more
wiley   +1 more source

Selection of suppliers in an alternative food network

International Review
In this study, the selection of suppliers within an alternative food supply network for fruits and vegetables, specifically Box Schemes, was conducted using multi-criteria decision-making methods. The Entropy-MABAC method was used as the multi-criteria decision-making approach, and the research focused on five suppliers from the city of Novi Sad ...
Miroslav Nedeljković, Adis Puška, Aleksandra Ćirković   +2 more
openaire   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

Arthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni, Lee Shapiro, Deana Gibbs, Zsuzsanna H. McMahan, Michael Hughes   +4 more
wiley   +1 more source

Dynamic evaluation of distribution channels in a fresh food supply chain from a sustainability and resilience approach

Alexandria Engineering Journal
Research on agrifood supply chains has grown in recent years; however, little attention has been given to the effect of the choice of distribution channel on the sustainable and resilient performance of the network.
Andrés Mauricio Paredes-Rodríguez, Juan Carlos Osorio-Gómez, Juan Pablo Orejuela-Cabrera   +2 more
doaj   +1 more source