Results 151 to 160 of about 2,258,983 (316)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Self-administered complementary and alternative methods of treating mental disorders among students in Wrocław: a cross-sectional study. [PDF]

Front Public Health
Sobieraj J, Sleziak J, Szyszka M, Błażejewska M, Łukańko K, Soczomska P, Bodziony K, Piotrowski P.   +7 more
europepmc   +1 more source

Empirical assessment of alternative methods for identifying seasonality in observational healthcare data. [PDF]

BMC Med Res Methodol, 2022
Molinaro A, DeFalco F.
europepmc   +1 more source

Review: Alternative data collection and analysis methods for disaster reconnaissance [PDF]

Yasemin D. Aktaş, Emily So
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

A cost-utility analysis for return-to-work interventions comparing alternative methods for handling missing health-related quality of life data. [PDF]

J Rehabil Med
Nguyen C, Burger EA, Aasdahl L, Morgante N, Fimland MS, Bjørnelv GMW.   +5 more
europepmc   +1 more source

Assessment of three alternative methods for bacterial disinfection of hatching eggs in comparison with conventional approach in commercial broiler hatcheries. [PDF]

PLoS One, 2023
Motola G, Hafez HM, Brüggemann-Schwarze S.   +2 more
europepmc   +1 more source

Impact of Alternative Regeneration Methods on Genetic Diversity in Coastal Douglas-Fir [PDF]

, 1998
W. T. Adams, Jinghua Zuo, J. Y. Shimizu, John C. Tappeiner   +3 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Alternative methods for analyzing cross-sectional studies of common outcomes: A guide for healthcare professionals. [PDF]

J Taibah Univ Med Sci
Aljawadi MH.
europepmc   +1 more source