Results 161 to 170 of about 2,258,983 (316)

Face-to-face and online teaching experience on experimental animals and alternative methods with nursing students: a research study. [PDF]

BMC Nurs, 2023
Garcia Sierra JF, Fernandez Martinez MN, Lopez Cadenas C, Diez Laiz R, Rodriguez Lago JM, Sahagun Prieto AM.   +5 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Global progress in competitive co-evolution: a systematic comparison of alternative methods. [PDF]

Front Robot AI
Nolfi S, Pagliuca P.
europepmc   +1 more source

Development of Synthetic Aqueous Oil and Grease Standards for Determination of TOG in Produced Water: Evaluation of Alternative Methods for Application in an Offshore Environment. [PDF]

ACS Omega, 2023
Ferraço Brant V, Carvalho RM, Martins MO, Marques FFC, Fidalgo-Neto AA.   +4 more
europepmc   +1 more source

Alternative financing mechanisms for ART programs in health facilities in Uganda: a mixed-methods approach [PDF]

, 2017
Henry Zakumumpa, Sara Bennett, Freddie Ssengooba   +2 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Beyond IV push: alternative methods for management of acute pain in SCD. [PDF]

Hematology Am Soc Hematol Educ Program
Azul M, Brandow AM.
europepmc   +1 more source

A review of alternative methods to the use of animals in safety evaluation of cosmetics. [PDF]

Einstein (Sao Paulo), 2022
Nabarretti BH, Rigon RB, Burga-Sánchez J, Leonardi GR.   +3 more
europepmc   +1 more source

13С urease breath test as a method for Helicobacter pylori infection control in case of using traditional and alternative eradication techniques

, 2017
С. И. Рапопорт, Nina A. Shubina   +1 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source