Results 171 to 180 of about 2,258,983 (316)

Alternative Methods of Fixation for Anterior Tibialis Transfer in Residual Clubfoot Deformity. [PDF]

J Pediatr Soc North Am
Wilson S, Bellaire LL, Noonan KJ.
europepmc   +1 more source

Alternative methods for skeletal maturity estimation with the EOS scanner-Experience from 934 patients. [PDF]

PLoS One, 2022
Schlégl ÁT, O'Sullivan I, Varga P, Than P, Vermes C.   +4 more
europepmc   +1 more source

Alternative Method for Primary Nasal Epithelial Cell Culture Using Intranasal Brushing and Feasibility for the Study of Epithelial Functions in Allergic Rhinitis

, 2015
Do‐Yang Park, Su-Jin Kim, Chang‐Hoon Kim, Joo‐Heon Yoon, Hyun-Jik Kim   +4 more
openalex   +1 more source

Earnings Penalty of Educational Mismatch: A Comparison of Alternative Methods of Assessing Over-Education

, 2023
Le Wen, Sholeh A. Maani
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Pig welfare and ethical considerations during abattoir stunning: CO₂ vs. alternative methods such as argon gas. [PDF]

Front Vet Sci
Mace JL, Knight A.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The Progression-Free-Survival Ratio in Molecularly Aided Tumor Trials: A Critical Examination of Current Practice and Suggestions for Alternative Methods. [PDF]

Biom J
Edelmann D, Terzer T, Horak P, Schlenk R, Benner A.   +4 more
europepmc   +1 more source

Alternative Methods to Current In Vivo Procedures to Address the 3Rs Tenet in Rabies Proficiency Testing. [PDF]

Viruses, 2022
Zorzan M, Gourlaouen M, Leopardi S, De Benedictis P.   +3 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source