Results 171 to 180 of about 248,399 (331)

Oncolytic Probiotics with Molecular Pili for Solid Tumor Therapy

Advanced Science, EarlyView.
This study identifies Lactobacillus rhamnosus as an intrinsic oncolytic agent that triggers tumor metabolic collapse via calcium‐dependent ROS bursts. By chemically anchoring collagen‐targeting “molecular pili” to the bacterial surface, the engineered non‐transgenic probiotic (LR@MP) achieves targeted colonization and potent solid tumor suppression ...
Haodong Ge, Chengsheng Ding, Xiao Yang, Si Gao, Changjie Yang, Yuchen Hou, Hongye Wang, Linke Bian, Hao Zhong, Yifan Qu, Luyang Zhang, Junjun Ma, Zhengwei Cai, Wenguo Cui, Minhua Zheng   +14 more
wiley   +1 more source

Mutations in the Second Alternative Oxidase Gene: A New Approach to Group Aspergillus niger Strains. [PDF]

J Fungi (Basel), 2023
Flipphi M, Márton A, Bíró V, Ág N, Sándor E, Fekete E, Karaffa L, Karaffa L.   +7 more
europepmc   +1 more source

Modified alternative oxidase expression results in different reactive oxygen species content in Arabidopsis cell culture but not in whole plants [PDF]

, 2012
В. И. Тарасенко, E. Yu. Garnik, В. Н. Шмаков, Yu. M. Konstantinov   +3 more
openalex   +1 more source

Structure of the Plant Alternative Oxidase [PDF]

Journal of Biological Chemistry, 2002
Mary S. Albury, Charles Affourtit, Paul G. Crichton, Anthony L. Moore   +3 more
openaire   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

Advanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen, Xinkai Pu, Ruiyang Li, Yuezhou Wu, Qirong Zhou, Jian Wang, Yuxuan Qian, Fengjie Lu, Jian‐Yuan Zhao, Zhida Su, Jiacan Su, Xiaofeng Lian   +11 more
wiley   +1 more source

Inhibition of alternative oxidase disrupts the development and oviposition of Biomphalaria glabrata snails. [PDF]

Parasit Vectors, 2023
Xu S, Zhang YW, Habib MR, Li SZ, Yuan Y, Ke WH, Jiang N, Dong H, Zhao QP.   +8 more
europepmc   +1 more source

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source

Localization and functional characterization of the alternative oxidase in Naegleria. [PDF]

J Eukaryot Microbiol, 2022
Cantoni D, Osborne A, Taib N, Thompson G, Martín-Escolano R, Kazana E, Edrich E, Brown IR, Gribaldo S, Gourlay CW, Tsaousis AD.   +10 more
europepmc   +1 more source

Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. [PDF]

, 2002
We show here the transient activation of the small GTPase Rac, followed by a rise in reactive oxygen species (ROS), as necessary early steps in a signal transduction cascade that lead to NFkappaB activation and collagenase-1 (CL-1)/matrix ...
Werb, Zena, Werner, Erica
core  

Lewis Pair‐Engineered CuMnOx as Cold‐Adapted Multinanozyme for Cooperative Hydrolytic and Oxidative Degradation of Raw Corn Stalk

Advanced Science, EarlyView.
A Lewis pair site design strategy was established to construct Cu‐doped Mn‐based amorphous nanozymes, where Mn and oxygen vacancies generate cooperative acid‐base pairs. The resulting multinanozyme integrates glycosidase‐, oxidase‐, and cold‐adapted enzyme‐mimicking activities, enabling cooperative depolymerization of cellulose and hemicellulose ...
Huile Liu, Ziyi Di, Qing Tian, Yue Zhou, Rong Yang, Zhiyi Bai, Haoyu Wang, Yao Chen, Lianbing Zhang   +8 more
wiley   +1 more source