Results 181 to 190 of about 248,399 (331)

Self‐Sustaining Piezozyme Platform for Antifouling via Mechanically Triggered Enzymatic Cascade

open access: yesAdvanced Science, EarlyView.
Wave‐powered CeO2/g‐C3N4 piezozyme coating converts ocean motion into an enzymatic H2O2‐to‐ROS cascade, realizing 180‐day eco‐friendly marine antifouling. ABSTRACT Harnessing ubiquitous mechanical energy for catalytic activation offers an emerging pathway toward self‐sustaining environmental protection systems.
Jingyu Wang   +3 more
wiley   +1 more source

Multifactor transcriptional control of alternative oxidase induction integrates diverse environmental inputs to enable fungal virulence. [PDF]

open access: yesNat Commun, 2023
Liu Z   +7 more
europepmc   +1 more source

Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang   +8 more
wiley   +1 more source

Biomimetic Ru‐Mn Nanozyme with Cascade Catalytic Activity Attenuates Secondary Brain Injury in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan   +8 more
wiley   +1 more source

Synergistic Enhancement of Catalytic Activities in Ligand‐Regulated Carbon Dots‐Ferric Ion Nanozymes via UV‐Enhanced Peroxidase‐Oxidase

open access: yesAdvanced Science, EarlyView.
Three CDs‐Fe nanozymes functionalized with tailor‐made ligands (TPP, HEDP, and DTPA) are synthesized via hydrothermal carbonization and coordination chemistry. A ligand‐regulation strategy for CDs‐Fe nanozymes achieves tunable enzyme‐mimicking activities and a powerful synergistic effect between POD and UV‐induced OXD pathways, paving the way for ...
Xiangli Li   +4 more
wiley   +1 more source

Multi‐Organelle Stress‐Induced Paraptosis by a ROS‐Amplifying Nanocatalyst for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu   +9 more
wiley   +1 more source

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