Alternative oxidase‐mediated respiration prevents lethal mitochondrial cardiomyopathy
EMBO Molecular Medicine, 2018 Alternative oxidase (AOX) is a non‐mammalian enzyme that can bypass blockade of the complex III‐IV segment of the respiratory chain (RC). We crossed a Ciona intestinalis AOX transgene into RC complex III (cIII)‐deficient Bcs1lp.S78G knock‐in mice ...
Jayasimman Rajendran +14 more
doaj +7 more sources
The Complementary Roles of Chloroplast Cyclic Electron Transport and Mitochondrial Alternative Oxidase to Ensure Photosynthetic Performance [PDF]
Frontiers in Plant Science, 2021 Chloroplasts use light energy and a linear electron transport (LET) pathway for the coupled generation of NADPH and ATP. It is widely accepted that the production ratio of ATP to NADPH is usually less than required to fulfill the energetic needs of the ...
Avesh Chadee +3 more
doaj +2 more sources
Structural and Biophysical Characterization of Purified Recombinant Arabidopsis thaliana's Alternative Oxidase 1A (rAtAOX1A): Interaction With Inhibitor(s) and Activator [PDF]
Frontiers in Plant Science, 2022 In higher plants, alternative oxidase (AOX) participates in a cyanide resistant and non-proton motive electron transport pathway of mitochondria, diverging from the ubiquinone pool. The physiological significance of AOX in biotic/abiotic stress tolerance
Tadiboina Veera Sankar +5 more
doaj +2 more sources
The mitochondrial alternative oxidase Aox1 is needed to cope with respiratory stress but dispensable for pathogenic development in Ustilago maydis. [PDF]
PLoS ONE, 2017 The mitochondrial alternative oxidase is an important enzyme that allows respiratory activity and the functioning of the Krebs cycle upon disturbance of the respiration chain.
Christian A Cárdenas-Monroy +6 more
doaj +2 more sources
Alternative oxidase involvement in Daucus carota somatic embryogenesis [PDF]
Physiologia Plantarum, 2009 Plant alternative oxidase (AOX) is a mitochondrial inner membrane enzyme involved in alternative respiration.The critical importance of the enzyme during acclimation upon stress of plant cells is not fully understood and is still an issue of intensive ...
Arnholdt-Schmitt, Birgit +4 more
core +4 more sources
Alternative oxidase in bacteria.
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2022 While alternative oxidase (AOX) was discovered in bacteria in 2003, the expression, function, and evolutionary history of this protein in these important organisms is largely unexplored. To date, expression and functional analysis is limited to studies in the Proteobacteria Novosphingobium aromaticivorans and Vibrio fischeri, where AOX likely plays ...
Anne K. Dunn
semanticscholar +3 more sources
Analysis of Posttranslational Activation of Alternative Oxidase Isoforms1[OPEN] [PDF]
Plant Physiology, 2017 The multiple alternative oxidase isoforms from Arabidopsis are differentially activated by various metabolites, suggesting isoform-specific functions.
Jennifer Selinski +5 more
semanticscholar +3 more sources
Alternative Oxidase Alleviates Mitochondrial Oxidative Stress during Limited Nitrate Reduction in Arabidopsis thaliana [PDF]
BiomoleculesThe conversion of nitrate to ammonium, i.e., nitrate reduction, is a major consumer of reductants in plants. Previous studies have reported that the mitochondrial alternative oxidase (AOX) is upregulated under limited nitrate reduction conditions ...
Daisuke Otomaru +6 more
doaj +2 more sources
Bilirubin oxidase from myrothecium verrucaria physically absorbed on graphite electrodes. Insights into the alternative resting from and the sources of activity loss [PDF]
, 2015 The oxygen reduction reaction is one of the most important chemical processes in energy converting systems and living organisms. Mediator-less, direct electro-catalytic reduction of oxygen to water was achieved on spectrographite electrodes modified by
Carmen Castro +4 more
core +18 more sources
Alternative oxidase and plant stress tolerance [PDF]
Plant Signaling & Behavior, 2016 Alternative oxidase (AOX) is one of the terminal oxidases of the plant mitochondrial electron transport chain. AOX acts as a means to relax the highly coupled and tensed electron transport process in mitochondria thus providing and maintaining the much needed metabolic homeostasis by directly reducing oxygen to water.
Bedabrata Saha +2 more
semanticscholar +3 more sources