The Relationships Among an Activity of the Alternative Pathway Respiratory Flux, a Content of Carbohydrates and a Frost-Resistance of Winter Wheat [PDF]
Journal of Stress Physiology & Biochemistry, 2013 A content of carbohydrates and dehydrins in the leaves, activities of the alternative (AP) and the cytochrome (CP) pathways of respiration in mitochondria, isolated from leaves, during cold hardening continuous light (5 °C) and dark conditions with ...
O.A. Borovik +4 more
doaj
Frontiers in Immunology, 2019 Properdin enhances complement-mediated opsonization of targeted cells and particles for immune clearance. Properdin occurs as dimers, trimers and tetramers in human plasma, which recognize C3b-deposited surfaces, promote formation, and prolong the ...
Ramon M. van den Bos +4 more
doaj +1 more source
Finding Thermodynamically Favorable Pathways in Reaction Networks using Flows in Hypergraphs and Mixed Integer Linear Programming [PDF]
arXivFinding pathways that optimize the formation of a particular target molecule in a chemical reaction network is a key problem in many settings, including reactor systems. Reaction networks are mathematically well represented as hypergraphs, a modeling that facilitates the search for pathways by computational means.
arxiv
Molecular Oncology, EarlyView.The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang +3 more
wiley +1 more source
Frontiers in Immunology, 2016 Neutrophils deposit antimicrobial proteins such as myeloperoxidase and proteases on chromatin, which they release as neutrophil extracellular traps (NETs). Neutrophils also carry key components of the complement alternative pathway (AP) such as properdin
Joshua eYuen +10 more
doaj +1 more source
LeaPP: Learning Pathways to Polymorphs through machine learning analysis of atomic trajectories [PDF]
arXivUnderstanding the mechanisms underlying crystal formation is crucial. For most systems, crystallization typically goes through a nucleation process that involves dynamics that happen at short time and length scales. Due to this, molecular dynamics serves as a powerful tool to study this phenomenon. Existing approaches to study the mechanism often focus
arxiv
Initiation of Bone Resorption by the Classical and Alternative C Pathways and Its Mediation by Prostaglandins [PDF]
, 1977 Ann L. Sandberg +4 more
openalex +1 more source
Looking back on the alternative complement pathway [PDF]
Immunobiology, 2018 The alternative pathway of complement originated from the Properdin pathway originally described by the Pillemer laboratory in the 1950s. This work generated great controversy and it took several decades for a consensus on its components, its reaction sequence and its functions to emerge.
openaire +2 more sources
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Lactate: an alternative pathway for the immunosuppressive properties of mesenchymal stem/stromal cells. [PDF]
Stem Cell Res Ther, 2023 Pradenas C +21 more
europepmc +1 more source