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Alternative Complement Pathway in Schizophrenia [PDF]
Neurochemical Research, 2010 In the present study, we evaluated functional activity of the alternative pathway of complement in schizophrenia by measuring the alternative pathway hemolytic activity (AH50) of complement as well as hemolytic activity of the complement C3 component (C3H50) in the blood of patients with schizophrenia and healthy subjects.
Andranik Chavushyan +2 more
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An ‘Alternative’ Pathway of T Cell Activation [PDF]
International Archives of Allergy and Immunology, 1994 T cell receptor mediated signals in T cell activation determine the specificity, while costimulatory/accessory signals are responsible for functional results of the immune response. Given the large number of accessory receptors in the T cell membrane, there exists a potent instrument to fine-tune immune reactions.
Burkhart Schraven +2 more
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Alternative pathway amplification and infections
Immunological Reviews, 2022SummaryThe alternative pathway (AP) is the phylogenetically oldest arm of the complement system and may have evolved to mark pathogens for elimination by phagocytes. Studies using purified AP proteins or AP‐specific serum showed that C3b amplification on bacteria commenced following a lag phase of about 5 min and was highly dependent on the ...
Jutamas Shaughnessy +3 more
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Science, 2004
IMMUNOLOGY Cell-surface receptors in the signaling lymphocyte activation molecule (SLAM) family play diverse roles in the lives of T and B lymphocytes, NK cells, dendritic cells, and macrophages.
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IMMUNOLOGY Cell-surface receptors in the signaling lymphocyte activation molecule (SLAM) family play diverse roles in the lives of T and B lymphocytes, NK cells, dendritic cells, and macrophages.
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Alternating Views on the ABR Alternate Pathway
RadiologyThe alternate pathway to American Board of Radiology certification has recently gained traction among international graduates; drawing from personal experiences, we summarize the challenges candidates may face, hoping to prepare potential candidates for the hurdles ahead.
Adarsh Ghosh, Eric Crotty
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The Alternative Pathway of Complement Activation
1976Publisher Summary This chapter presents the alternative pathway of complement activation. Two pathways for the recruitment of complement and its biological activities exist in plasma and serum. The first is termed as the “classical pathway,” which is triggered by contact of C1 with immune complexes containing antibodies of the immunoglobulin G (IgG ...
Otto Götze, Hans J. Müller-Eberhard
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Alternative Pathways to Certification
2019This chapter explores the literature on alternative pathways to teacher certification to provide a context for understanding how and why these programs developed and their potential impact on traditional pathways to licensure. A discussion of the different types of alternative certification programs, including graduate-level teacher certification ...
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2007
There are four members of the mammalian p38 mitogen-activated protein kinases (MAPKs) family (p38α, p38β, p38γ, and p38δ) which are about 60% identical in their amino acid sequence but differ in their expression patterns, substrate specificities, and sensitivities to chemical inhibitors such as SB203580.
Ana Cuenda +3 more
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There are four members of the mammalian p38 mitogen-activated protein kinases (MAPKs) family (p38α, p38β, p38γ, and p38δ) which are about 60% identical in their amino acid sequence but differ in their expression patterns, substrate specificities, and sensitivities to chemical inhibitors such as SB203580.
Ana Cuenda +3 more
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Science, 2011
Biochemistry The low-molecular-weight thiol glutathione (GSH) is essential for growth in eukaryotes and plays a central role in stress responses and the maintenance of redox homeostasis in certain bacteria. Surprisingly, most aerobic bacteria lack the GSH biosynthesis enzyme glutamate cysteine ligase (GshA), although many have genes encoding proteins ...
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Biochemistry The low-molecular-weight thiol glutathione (GSH) is essential for growth in eukaryotes and plays a central role in stress responses and the maintenance of redox homeostasis in certain bacteria. Surprisingly, most aerobic bacteria lack the GSH biosynthesis enzyme glutamate cysteine ligase (GshA), although many have genes encoding proteins ...
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Alternative protein sorting pathways
2000The term "nonclassical protein targeting" has been used to describe those pathways that have been recently discovered and differ mechanistically from the more studied "classical pathways." Because this nomenclature is rather arbitrary in terms of cellular relevance, we have chosen to group these protein sorting mechanisms under the heading "alternative
Sidney V. Scott +2 more
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