Results 131 to 140 of about 28,556 (226)

Exploring the Role of Long Noncoding RNAs in Breast Cancer Progression: A Comprehensive Study on Biomarkers and Therapeutic Approaches

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Among the many forms of cancer that plague women all over the globe, breast cancer (BC) is one of the most prevalent kinds. BC is a multifaceted disease that can manifest in many ways depending on the individual. Aims The identification of new biomarkers that may be used to diagnose and prognosis of the BC, as well as those that can
Ramin Moeini, Amin AhsanAlkhat, Saeid Ghorbian   +2 more
wiley   +1 more source

Long non‐coding RNA lncAPAT promotes atherosclerotic plaque instability by targeting ribosomal protein L22

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
LncAPAT interacted with the promoter region of RPL22 to inhibit RPL22 transcriptional activity and increase the expression of MCP‐1, thereby contributing to plaque instability. Abstract Background Long non‐coding RNAs (lncRNAs) regulate macrophage inflammation and atherosclerotic plaque stability, but mechanisms need comprehensive investigations ...
Rongxia Li, Qiyue Zhang, Yu Chen, Shuting Wang, Shuang Han, Adalaiti Kamili, Yixuan Zhong, Shujun Yang, Weili Zhang   +8 more
wiley   +1 more source

Complete Mitochondrial Genomes Recovered From Environmental Metagenomics Samples Can Facilitate Non‐Intrusive Population Genetic/Genomics Studies in the South American Sea Lion Otaria byronia

Environmental DNA, Volume 8, Issue 1, January–February 2026.
Mitochondrial genomes assembled from environmental non‐intrusive fecal DNA to support non‐intrusive biomonitoring in the Southern Sea Lion Otaria byronia. Photograph by Nestor Galina, used with permission. ABSTRACT The abundance of many marine mammals is declining due to local, regional, and global climate stressors that characterize the Anthropocene ...
Juan Antonio Baeza, Angélica Colín, Maryam Dehghanian, Eduardo Castro‐Nallar, Simon Berents   +4 more
wiley   +1 more source

Alternative polyadenylation confers PtenmRNAs stability and resistance to microRNAs [PDF]

, 2018
Caroline Thivierge, Hsin-Wei Tseng, Vinay K. Mayya, Carine Lussier, Simon‐Pierre Gravel, Thomas F. Duchaîne   +5 more
openalex   +1 more source

Data from Targeting a Single Alternative Polyadenylation Site Coordinately Blocks Expression of Androgen Receptor mRNA Splice Variants in Prostate Cancer

, 2023
Jamie L. Van Etten, Michael D. Nyquist, Yingming Li, Rendong Yang, Yeung Ho, Rachel K. Johnson, Olivia Ondigi, Daniel F. Voytas, Christine Henzler, Scott M. Dehm   +9 more
openalex   +1 more source

DeeReCT-APA: Prediction of Alternative Polyadenylation Site Usage Through Deep Learning [PDF]

, 2020
Zhongxiao Li, Yisheng Li, Bin Zhang, Yu Li, Yongkang Long, Juexiao Zhou, Xudong Zou, Min Zhang, Yuhui Hu, Wei Chen, Xin Gao   +10 more
openalex   +1 more source

Cell-type-specific alternative polyadenylation as a therapeutic biomarker in lung cancer progression [PDF]

, 2023
Kang Li, Min Qiang, Yungang Xu
openalex   +1 more source

Rps19R67∆ mutation creates a model of Diamond–Blackfan anemia and reveals downstream mediators of p53 pathway

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Diamond–Blackfan anemia (DBA) is a rare bone marrow failure syndrome accompanied by cardiovascular, skeletal, and urogenital abnormalities. Most of the affected individuals carry mutations in ribosomal proteins, including RPS19, a component of the 40S ribosomal subunit.
Juraj Kokavec, Tereza Turková, Björn Schuster, Jan Prochazka, František Spoutil, Kristína Jamrichová, Markéta Holečková, Karel Chalupský, Inken M. Beck, Jesús Ruberte, Matilde Vale, Lukáš Čermák, Tomáš Stopka, Radislav Sedlacek   +13 more
wiley   +1 more source

Deciphering Estrus Expression in Gilts: The Role of Alternative Polyadenylation and LincRNAs in Reproductive Transcriptomics

Animals
The fertility rate and litter size of female pigs are critically affected by the expression of estrus. The objective of this study was to elucidate the regulatory mechanisms of estrus expression by analyzing the differential expression of genes and long ...
Mingzheng Liu, Jiahao Chen, Chunlei Zhang, Shuhan Liu, Xiaohuan Chao, Huan Yang, Asim Muhammad, Bo Zhou, Weiping Ao, Allan P. Schinckel   +9 more
doaj   +1 more source

Cross‐Species Insights Into Gamma Herpesvirus Transcriptomes: Long‐Read and Multi‐Omics Perspectives

Journal of Medical Virology, Volume 98, Issue 1, January 2026.
ABSTRACT Comparative transcriptome analyses of gamma herpesviruses have been revolutionized by long‐read sequencing and integrative multi‐omics approaches, enabling unprecedented resolution of viral gene expression. Cross‐species studies of Kaposi's sarcoma‐associated herpesvirus (KSHV), Epstein–Barr virus (EBV), and murine gamma herpesvirus 68 (MHV68)
Ritu Shekhar, Sarah McMahon, Scott A. Tibbetts, Erik K. Flemington, Rolf Renne   +4 more
wiley   +1 more source