Results 241 to 250 of about 1,685,857 (295)

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Transcriptome assemblies for two drug-type cannabis chemotypes by long-read RNA sequencing. [PDF]

Plant Genome
Berkowitz O, Jost R, Ng S, Bacic A, Whelan J, Lewsey MG.   +5 more
europepmc   +1 more source

ConforFold recovers alternative protein conformations beyond MSA subsampling. [PDF]

Protein Sci
Syrlybaeva R, Strauch EM.
europepmc   +1 more source

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Alternative Proteins

2021
In the last decade, there has been substantial research dedicated towards prospecting physiochemical, nutritional and health properties of novel protein sources. In addition to being driven by predictions of increased population and lack of a parallel increase in traditional protein sources, main drivers for the rise in novel proteins/ novel foods ...
Bekhit, Alaa, Riley, William W., Hussain, Malik A. (R20588)   +2 more
openaire   +2 more sources

Alternative scaffold proteins

Russian Journal of Bioorganic Chemistry, 2011
Review is devoted to the challenging direction in modem molecular biology and bioengineering - the properties of alternative scaffold proteins (ASP) and methods for obtaining ASP binding molecules. ASP molecules incorporate conservative protein core and hypervariable regions, providing for the binding function. Structural classification of ASP includes
L E, Petrovskaia, L N, Shingarova, D A, Dolgikh, M P, Kirpichnikov   +3 more
openaire   +2 more sources

Alternative ribosomes synthesize alternative proteins

The FASEB Journal, 2016
In addition to the complete set of ribosomal proteins needed to form ribosomes, many bacteria have at least one duplicated (i.e., alternative) ribosomal protein. It has been suggested that alternative ribosomal proteins (AltRP) in Bacillus subtilis and Escherichia coli
Allexa Dow, Sladjana Prisic
openaire   +1 more source

Sustainable protein alternatives

Trends in Food Science & Technology, 2021
Abstract Background Fake meat industry is expected to grow and to be worth $140 billion by 2030. Alternative protein can be produced by plant or microbe. Animal-free dairy protein can be produced by fermentation in microflora. Scope and approach In order to improve the real production, many companies are focusing on fermentation for animal-free ...
openaire   +1 more source

Meet the Meat Alternatives: The Value of Alternative Protein Sources

Current Nutrition Reports, 2020
Meat alternatives are non-animal-based proteins with chemical characteristics and aesthetic qualities comparable to meat. The global increase in meat consumption is associated with the adverse environmental impacts such as increased greenhouse gas emissions contributing to global warming and higher water/land use.
Aravind Thavamani, Thomas J Sferra, Senthilkumar Sankararaman   +2 more
openaire   +2 more sources