Results 11 to 20 of about 3,932,181 (346)
Alternative Splicing in Angiogenesis
International Journal of Molecular Sciences, 2019 Alternative splicing of pre-mRNA allows the generation of multiple splice isoforms from a given gene, which can have distinct functions. In fact, splice isoforms can have opposing functions and there are many instances whereby a splice isoform acts as an
E. Bowler, S. Oltean
semanticscholar +4 more sources
Splicing and alternative splicing in rice and humans [PDF]
BMB Reports, 2013 Rice is a monocot gramineous crop, and one of the mostimportant staple foods. Rice is considered a model species formost gramineous crops. Extensive research on rice hasprovided critical guidance for other crops, such as maize andwheat.
Zhiguo E, Lei Wang, Jianhua Zhou
doaj +4 more sources
Alternative Splicing and Cancer
Journal of Nucleic Acids, 2012 Alternative splicing of premessenger RNAs is a key step in the gene expression process, which allows the synthesis of different products from the same gene and contributes to increase the complexity of the proteome coded by a limited number of genes. Specialized high-throughput technologies (RNA-Seq, splicing-sensitive microarrays) aiming at analyzing ...
Didier Auboeuf +3 more
doaj +4 more sources
Temporal Dynamic Analysis of Alternative Splicing During Embryonic Development in Zebrafish
Frontiers in Cell and Developmental Biology, 2022 Alternative splicing is pervasive in mammalian genomes and involved in embryo development, whereas research on crosstalk of alternative splicing and embryo development was largely restricted to mouse and human and the alternative splicing regulation ...
Zhe Liu +11 more
doaj +1 more source
Alternative splicing during fruit development among fleshy fruits
BMC Genomics, 2021 Background Alternative splicing (AS) is an important mechanism of posttranscriptional modification and dynamically regulates multiple physiological processes in plants, including fruit ripening.
Xiaomin Yan +4 more
doaj +1 more source
Chromatin and Alternative Splicing [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2010 Alternative splicing affects more than 90% of human genes. Coupling between transcription and splicing has become crucial in the complex network underlying alternative splicing regulation. Because chromatin is the real template for nuclear transcription, changes in its structure, but also in the "reading" and "writing" of the histone code, could ...
Alló, M. +7 more
openaire +4 more sources
Alternative splicing and cancer: a systematic review
Signal Transduction and Targeted Therapy, 2021 The abnormal regulation of alternative splicing is usually accompanied by the occurrence and development of tumors, which would produce multiple different isoforms and diversify protein expression. The aim of the present study was to conduct a systematic
Yuan-jiao Zhang +3 more
semanticscholar +1 more source
Alternative Splicing and Isoforms: From Mechanisms to Diseases
Genes, 2022 Alternative splicing of pre-mRNA is a key mechanism for increasing the complexity of proteins in humans, causing a diversity of expression of transcriptomes and proteomes in a tissue-specific manner.
Qi Liu, Leiming Fang, Chengjun Wu
semanticscholar +1 more source
Alternative Splice in Alternative Lice [PDF]
Molecular Biology and Evolution, 2015 Genomic and transcriptomics analyses have revealed human head and body lice to be almost genetically identical; although con-specific, they nevertheless occupy distinct ecological niches and have differing feeding patterns. Most importantly, while head lice are not known to be vector competent, body lice can transmit three serious bacterial diseases ...
Tovar-Corona, Jaime M. +8 more
openaire +2 more sources
Rice, 2021 Alternative splicing is a widespread phenomenon, which generates multiple isoforms of the gene product. Reproductive development is the key process for crop production. Although numerous forms of alternative splicing have been identified in model plants,
Haoxuan Li +5 more
doaj +1 more source