Results 231 to 240 of about 336,398 (336)

Functional differences among alternatively spliced variants of Slowpoke, a Drosophila calcium-activated potassium channel.

, 1994
Armando Lagrutta, K.Z. Shen, R A North, John P. Adelman   +3 more
openalex   +1 more source

Modulation of alternative splicing of adenoviral E1A transcripts: factors involved in the early-to-late transition. [PDF]

, 1991
Renata Gattoni, K. Chebli, Michèle Himmelspach, James Stévenin   +3 more
openalex   +1 more source

Dimer‐Specific FokT‐seq Reveals DNA‐Binding Dimerization and Novel Genomic Targets of TDP‐43

Advanced Science, EarlyView.
Loss of TDP‐43 dimerization is implicated in ALS, yet its mechanistic role remains elusive. This study introduces FokT, a novel system that restores TDP‐43 dimerization to map its DNA targets via FokT‐seq. The findings uncover key binding sites and offer a versatile tool for exploring dimer‐dependent transcriptional regulation.
Mingming Yang, Qi Wang, Ruolan Yan, Xiaochuan Wang, Jianlan Gu   +4 more
wiley   +1 more source

Alternative splicing repurposes the Drosophila mitotic regulator Mud for meiotic functions. [PDF]

Genetics
Finegan TM, Deem K, Tan R, Lowe N, Weeks N, Linhoff MW, Wang X, López-Molini I, Benraiss A, Bergstralh DT.   +9 more
europepmc   +1 more source

Human alpha 3(VI) collagen gene. Characterization of exons coding for the amino-terminal globular domain and alternative splicing in normal and tumor cells

, 1991
David G. Stokes, B. Saitta, Rupert Timpl, Mon‐Li Chu   +3 more
openalex   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

Advanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei, Zongzheng Zhao, Ruoqi Xu, Qin Yan, Liangzi Jiang, Fuxiao Geng, Yang Gu, Tianjiao Wang, Jing Zhou, Xiao Li, Qin Yan, Chun Lu, Wan Li   +12 more
wiley   +1 more source

In-vitro human myogenesis model reveals novel mRNA alternative splicing isoforms. [PDF]

Sci Rep
Donega S, Banskota N, Yang JH, Rossi M, Piao Y, Tsitsipatis D, Fan J, De S, Peterson CA, McDermott MM, Gorospe M, Ferrucci L.   +11 more
europepmc   +1 more source

Developmentally regulated alternative splicing generates a complex array of Drosophila para sodium channel isoforms [PDF]

, 1994
J. R. Thackeray, Barry Ganetzky
openalex   +1 more source

Integrative Omics Reveal Female‐Specific Benefits of p16+ Cell Clearance in Aging Mice

Advanced Science, EarlyView.
Aging causes accumulation of p16⁺ senescent cells that promote inflammation and dysfunction. Multi‐omics analyses reveal striking sex differences in senescent cell burden and clearance: females accumulate more p16⁺ cells, especially in the liver, and their removal rejuvenates molecular and functional profiles.
Yao Lin, Boshi Wang, Mengling Huang, Justina C. Wolters, Marco Demaria   +4 more
wiley   +1 more source

Functional analysis of alternatively spliced transcripts of the human histidine decarboxylase gene and its expression in human tissues and basophilic leukemia cells [PDF]

, 1992
Ruriko MAMUNE‐SATO, Kohei Yamauchi, Yasuo Tanno, Yuichi Ohkawara, Hiroshi Ohtsu, Dai Katayose, Kazutaka Maeyama, Takehiko Watanabe, Shigeki Shibahara, Tamotsu Takishima   +9 more
openalex   +1 more source