Results 231 to 240 of about 326,335 (355)

A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing

Advanced Science, EarlyView.
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang, Zhengshuo Li, Run Zheng, Xiang Zheng, Jia Wang, Can Liu, Yangge Wu, Yuqing Wen, Chunlin Ou, Songqing Fan, Chenxiao Xu, Junrui Tian, Qun Yan, Hao Nan, Xiaodong Xu, Hui Wang, Qiu Peng, Jian Ma   +17 more
wiley   +1 more source

Modulation of Neurexins Alternative Splicing by Cannabinoid Receptors 1 (CB1) Signaling. [PDF]

Cells
Innocenzi E, Sciamanna G, Zucchi A, Medici V, Cesari E, Farini D, Elliott DJ, Sette C, Grimaldi P.   +8 more
europepmc   +1 more source

Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission [PDF]

, 1994
JW Janssen, WD Ludwig, Arndt Borkhardt, U Spadinger, Harald Rieder, Christa Fonatsch, DK Hossfeld, Jochen Harbott, AS Schulz, Reinald Repp   +9 more
openalex   +1 more source

Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules

Advanced Science, EarlyView.
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu, Xinran Liu, Mei Xue, Yushuo Xiao, Yuchen Chen, Rong Qiu, Di Wu, Yihao Zhou, Jiao Wang, Yan Yuan, Linwei Yu, Tianyi Shi, Yangkai Li, Hua Su, Hong Chen, Yong Liu, Kun Huang, Ling Zheng   +17 more
wiley   +1 more source

Plant-Fungi Mutualism, Alternative Splicing, and Defense Responses: Balancing Symbiosis and Immunity. [PDF]

Int J Mol Sci
Zhao X, Muhammad Aslam M, Chen M, Das D.
europepmc   +1 more source

Functional differences among alternatively spliced variants of Slowpoke, a Drosophila calcium-activated potassium channel.

, 1994
Armando Lagrutta, K.Z. Shen, R A North, John P. Adelman   +3 more
openalex   +1 more source

Multiple Rh messenger RNA isoforms are produced by alternative splicing [PDF]

, 1992
Caroline Le Van Kim, Baya Chérif‐Zahar, V Raynal, Isabelle Mouro-Chanteloup, Marc Lopez, JP Cartron, Yves Colin   +6 more
openalex   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Single cell and spatial alternative splicing analysis with Nanopore long read sequencing. [PDF]

Nat Commun
Fu Y, Kim H, Roy S, Huang S, Adams JI, Grimes SM, Lau BT, Sathe A, Ji HP, Zhang NR.   +9 more
europepmc   +1 more source

Cloning and characterization of alternatively spliced isoforms of rat tenascin. Platelet-derived growth factor-BB markedly stimulates expression of spliced variants of tenascin mRNA in arterial smooth muscle cells.

, 1994
David W. LaFleur, James A. Fagin, James S. Forrester, Stanley A. Rubin, Behrooz G. Sharifi   +4 more
openalex   +1 more source