Results 1 to 10 of about 185,877 (164)

The origin of RNA precursors on exoplanets. [PDF]

open access: yesSci Adv, 2018
Researchers identify an “abiogenesis zone,” outside of which the building blocks of life cannot form photochemically.
Rimmer PB   +5 more
europepmc   +7 more sources

Contribution of Small RNA Pathway to Interactions of Rice with Pathogens and Insect Pests

open access: yesRice, 2021
Small RNAs (sRNAs) are mainly classified into microRNAs (miRNAs) and small interfering RNAs (siRNAs) according to their origin. miRNAs originate from single-stranded RNA precursors, whereas siRNAs originate from double-stranded RNA precursors that are ...
Qin Feng   +3 more
doaj   +1 more source

The role of human Dicer-dsRBD in processing small regulatory RNAs. [PDF]

open access: yesPLoS ONE, 2012
One of the most exciting recent developments in RNA biology has been the discovery of small non-coding RNAs that affect gene expression through the RNA interference (RNAi) mechanism.
Christopher Wostenberg   +6 more
doaj   +1 more source

JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors

open access: yesInflammation and Regeneration, 2023
Background Rheumatoid arthritis (RA) is characterized by chronic inflammation and resultant cartilage/bone destruction because of aberrantly activated osteoclasts.
Shinya Yari   +8 more
doaj   +1 more source

ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers. [PDF]

open access: yesPLoS ONE, 2013
A growing list of microRNAs (miRNAs) show aberrant expression patterns in hepatocellular carcinoma (HCC), but the regulatory mechanisms largely remain unclear.
Wan-Hsin Liu   +7 more
doaj   +1 more source

The Role of Adipocyte Precursors in Development and Obesity

open access: yesFrontiers in Endocrinology, 2021
Maintenance of adipocyte precursors is critical for regulating metabolism and preventing obesity related disease. These precursors have been immortalized and studied in cellular models as well as—more recently—in animal models.
Tammy Ying   +3 more
doaj   +1 more source

Splicing of Messenger RNA Precursors

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1987
A general mechanism for the splicing of nuclear messenger RNA precursors in eukaryotic cells has been widely accepted. This mechanism, which generates lariat RNAs possessing a branch site, seems related to the RNA-catalyzed reactions of self-splicing introns.
Sharp, P. A.   +5 more
openaire   +6 more sources

Non-Coding RNA Analyses of Seasonal Cambium Activity in Populus tomentosa

open access: yesCells, 2022
Non-coding RNA, known as long non-coding RNA (lncRNA), circular RNA (circRNA) and microRNA (miRNA), are taking part in the multiple developmental processes in plants.
Huimin Xu   +10 more
doaj   +1 more source

MicroRNA-122 dependent binding of Ago2 protein to hepatitis C virus RNA is associated with enhanced RNA stability and translation stimulation. [PDF]

open access: yesPLoS ONE, 2013
Translation of Hepatitis C Virus (HCV) RNA is directed by an internal ribosome entry site (IRES) in the 5'-untranslated region (5'-UTR). HCV translation is stimulated by the liver-specific microRNA-122 (miR-122) that binds to two binding sites between ...
K Dominik Conrad   +6 more
doaj   +1 more source

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