MicroRNAs from saliva of anopheline mosquitoes mimic human endogenous miRNAs and may contribute to vector-host-pathogen interactions [PDF]
During blood feeding haematophagous arthropods inject into their hosts a cocktail of salivary proteins whose main role is to counteract host haemostasis, inflammation and immunity. However, animal body fluids are known to also carry miRNAs.
Arcà, Bruno +7 more
core +3 more sources
Pseudouridylation of yeast ribosomal precursor RNA
The pseudouridylation of ribosomal RNA of Saccharomyces carlsbergensis was investigated with respect to its timing during the maturation of rRNA and its sequence specificity. Analysis of 37-S RNA, the common precursor to 17-S, 5.8-S and 26-S rRNA and most probably the primary ribosomal transcript, shows that this RNA molecule contains already most if ...
R C, Brand +3 more
openaire +3 more sources
The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 angstrom resolution [PDF]
Maturation of tRNA precursors into functional tRNA molecules requires trimming of the primary transcript at both the 5' and 3' ends. Cleavage of nucleotides from the 3' stem of tRNA precursors, releasing nucleotide diphosphates, is accomplished in ...
Blagova, Elena V. +5 more
core +2 more sources
Components required for in vitro cleavage and polyadenylation of eukaryotic mRNA [PDF]
We have studied in vitro cleavage/polyadenylation of precursor RNA containing herpes simplex virus type 2 poly A site sequences and have analysed four RNA/protein complexes which form during in vitro reactions.
Clements, J.B. +3 more
core +1 more source
Secondary Methylation of Yeast Ribosomal Precursor RNA [PDF]
The timing of methylation of the ribosomal sequences of ribosomal precursor RNA (pre-rRNA) from the yeast Saccharomyces carlsbergensis was investigated by fingerprint analysis of the methylated oligonucleotides derived from the various precursors.
R C, Brand +4 more
openaire +2 more sources
ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin
Summary: β-Hemoglobinopathies can trigger rapid production of red blood cells in a process known as stress erythropoiesis. Cellular stress prompts differentiating erythroid precursors to express high levels of fetal γ-globin.
Mandy Y. Boontanrart +9 more
doaj +1 more source
1. Câncer arises gradually, preceded by histological, histochemical and cariometric (tetraploidism) or hyperdiploidism pictures which may be called morphological precursors of câncer. 2.
Aurélio Monteiro
doaj +1 more source
Alignment of the amino terminal amino acid sequence of human cytochrome c oxidase subunits I and II with the sequence of their putative mRNAs [PDF]
Thirteen of the first fifteen amino acids from the NH2-terminus of the primary sequence of human cytochrome c oxidase subunit I and eleven of the first twelve amino acids of subunit II have been identified by microsequencing procedures.
Attardi, Giuseppe +2 more
core +2 more sources
Hfq and RNase R Mediate rRNA Processing and Degradation in a Novel RNA Quality Control Process
RNA quality control pathways are critical for cell survival. Here, we describe a new surveillance process involved in the degradation of highly structured and stable ribosomal RNAs.
Ricardo F. dos Santos +4 more
doaj +1 more source
Structural determinants of Arabidopsis thaliana Hyponastic leaves 1 function in vivo. [PDF]
MicroRNAs have turned out to be important regulators of gene expression. These molecules originate from longer transcripts that are processed by ribonuclease III (RNAse III) enzymes. Dicer proteins are essential RNAse III enzymes that are involved in the
Paula Burdisso +5 more
doaj +1 more source

