Results 41 to 50 of about 2,192,206 (343)

ATF4 Regulates MYB to Increase γ-Globin in Response to Loss of β-Globin

Cell Reports, 2020
Summary: β-Hemoglobinopathies can trigger rapid production of red blood cells in a process known as stress erythropoiesis. Cellular stress prompts differentiating erythroid precursors to express high levels of fetal γ-globin.
Mandy Y. Boontanrart, Markus S. Schröder, Gautier M. Stehli, Marija Banović, Stacia K. Wyman, Rachel J. Lew, Matteo Bordi, Benjamin G. Gowen, Mark A. DeWitt, Jacob E. Corn   +9 more
doaj   +1 more source

The Genesis of Human Breast Cancer: Histological, Histochemical and Cariometric Studies: Proposition on the Genesis of Cancer

Revista Brasileira de Cancerologia, 2023
1. Câncer arises gradually, preceded by histological, histochemical and cariometric (tetraploidism) or hyperdiploidism pictures which may be called morphological precursors of câncer. 2.
Aurélio Monteiro
doaj   +1 more source

The type II poly(A)-binding protein PABP-2 is a downstream target of the "let-7" microRNA in the heterochronic pathway of "Caenorhabditis elegans" : mechanisms of microRNA-mediated gene silencing in "Caenorhabditis elegans" [PDF]

, 2012
microRNAs (miRNAs) are a large class of small, non-coding RNAs that post-transcriptionally regulate gene expression in animals, plants and protozoa. miRNAs are genomically encoded and transcribed by RNA polymerase II. Primary transcripts are sequentially
Hurschler, Benjamin
core   +1 more source

RNA-binding protein immunoprecipitation as a tool to investigate plant miRNA processing interference by regulatory proteins of diverse origin

Plant Methods, 2018
Background Due to the nature of viral RNA genomes, RNA viruses depend on many RNA-binding proteins (RBP) of viral and host origin for replication, dissemination and evasion of host RNA degradation pathways. Some viruses interfere with the microRNA (miRNA)
F. E. Marmisolle, M. L. García, C. A. Reyes   +2 more
doaj   +1 more source

Structural determinants of Arabidopsis thaliana Hyponastic leaves 1 function in vivo. [PDF]

PLoS ONE, 2014
MicroRNAs have turned out to be important regulators of gene expression. These molecules originate from longer transcripts that are processed by ribonuclease III (RNAse III) enzymes. Dicer proteins are essential RNAse III enzymes that are involved in the
Paula Burdisso, Fernando Milia, Arnaldo L Schapire, Nicolás G Bologna, Javier F Palatnik, Rodolfo M Rasia   +5 more
doaj   +1 more source

Purification of the cleavage and polyadenylation factor involved in the 3'-processing of messenger RNA precursors.

Journal of Biological Chemistry, 1991
Polyadenylation of messenger RNA precursors requires the nucleotide sequence AAUAAA and two factors: poly(A) polymerase and a specificity factor termed cleavage and polyadenylation factor (CPF).
S. Bienroth, E. Wahle, Clemens Suter-CrazzolaraS, W. Keller   +3 more
semanticscholar   +1 more source

Complete probabilistic analysis of RNA shapes

, 2006
Voß B, Giegerich R, Rehmsmeier M. Complete probabilistic analysis of RNA shapes. BMC Biology. 2006;4(1): 5.Background: Soon after the first algorithms for RNA folding became available, it was recognised that the prediction of only one energetically ...
Marc Rehmsmeier, Voß, Björn, Rehmsmeier, Marc, Björn Voß, Rehmsmeier Marc, Robert Giegerich, Giegerich, Robert, Giegerich Robert, Voß Björn   +8 more
core   +1 more source

Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I [PDF]

, 2010
Mammalian cleavage factor I (CF Im) is composed of two polypeptides of 25 kDa and either a 59 or 68 kDa subunit (CF Im25, CF Im59, CF Im68). It is part of the cleavage and polyadenylation complex responsible for processing the 39 ends of messenger RNA ...
Antje Ostareck-Lederer, Neuenkirchen, N., Ostareck-Lederer, Antje, Keller, W., Dettwiler, Sabine, Sabine Dettwiler, Fischer, Utz, Martin, Georges, Rüegsegger, U., Fischer, U., Georges Martin, Ashwin Chari, Blank, Diana, Diana Blank, Neuenkirchen, Nils, Blank, D., Utz Fischer, Chari, Ashwin, Ostareck-Lederer, A., Nils Neuenkirchen, Walter Keller, Chari, A., Ursula Rüegsegger, Dettwiler, S., Martin, G., Keller, Walter, Rüegsegger, Ursula   +26 more
core   +1 more source

Hfq and RNase R Mediate rRNA Processing and Degradation in a Novel RNA Quality Control Process

mBio, 2020
RNA quality control pathways are critical for cell survival. Here, we describe a new surveillance process involved in the degradation of highly structured and stable ribosomal RNAs.
Ricardo F. dos Santos, José M. Andrade, Joana Pissarra, Murray P. Deutscher, Cecília M. Arraiano   +4 more
doaj   +1 more source

A new yeast poly(A) polymerase complex involved in RNA quality control [PDF]

, 2005
Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors.
Sabine Dettwiler (27038), Arno Friedlein (27039), Keller Walter, Stepánka Vanácová, Vanacova, S., Blank Diana, Martin Georges, Gérard Keith, Keller, W., Sabine Dettwiler, Jeannette Wolf (27035), Langen, H., Keith, G., Diana Blank (27037), Vanˇácˇová Sˇteˇpánka, Vanácová Stepánka, Georges Martin, Hanno Langen, Diana Blank, Hanno Langen (27040), Gérard Keith (27041), Keith Gérard, Walter Keller (27042), Wolf, J., Jeannette Wolf, Blank, D., Arno Friedlein, Wolf Jeannette, Štěpánka Vaňáčová (27034), Walter Keller, Friedlein, A., Langen Hanno, Friedlein Arno, Dettwiler, S., Dettwiler Sabine, Georges Martin (27036), Martin, G.   +36 more
core   +1 more source