Results 21 to 30 of about 320,389 (303)

Argonaute-dependent small RNAs derived from single-stranded non-structured precursors

Frontiers in Genetics, 2014
A general feature of Argonaute-dependent small RNAs is their base-paired precursor structures, and precursor duplex structures are often required for confident annotation of miRNA genes.
Li-Ling eChak, Katsutomo eOkamura, Katsutomo eOkamura   +2 more
doaj   +1 more source

Detection and Phylogenetic Analysis of Group 1 Coronaviruses in South American Bats

Emerging Infectious Diseases, 2008
Bat coronaviruses (Bt-CoVs) are thought to be the precursors of severe acute respiratory syndrome coronavirus. We detected Bt-CoVs in 2 bat species from Trinidad.
Christine V.F. Carrington, Jerome E. Foster, Hua Chen Zhu, Jin Xia Zhang, Gavin J.D. Smith, Nadin Thompson, Albert J. Auguste, Vernie Ramkissoon, Abiodun A. Adesiyun, Yi Guan   +9 more
doaj   +1 more source

Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly

Nature Communications, 2023
The U2 snRNP recognizes the intron during spliceosome assembly. Here the authors report the high-resolution structures of two assembly precursors of human U2 snRNP and reveal that the RNA helicases DDX42 and DDX46 are mutually exclusive in terms of SF3B1-
Fenghua Yang, Tong Bian, Xiechao Zhan, Zhe Chen, Zhihan Xing, Nicolas A. Larsen, Xiaofeng Zhang, Yigong Shi   +7 more
doaj   +1 more source

Modulation of microRNA editing, expression and processing by ADAR2 deaminase in glioblastoma. [PDF]

, 2015
Background: ADAR enzymes convert adenosines to inosines within double-stranded RNAs, including microRNA (miRNA) precursors, with important consequences on miRNA retargeting and expression.
Alon, S, Eisenberg, E, Galardi, S, Galeano, F, Gallo, A., Locatelli, F, Polito, V, Presutti, Carlo, Raho, S, Tomaselli, S, Vincenti, S   +10 more
core   +2 more sources

Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila

Nature Communications, 2016
In Drosophila ovarian follicle cells, piRNAs generated from RNA precursors are processed in cytoplasmic Yb-bodies. The authors identify the exportin and the exon junction complexes as required to transfer precursors to cytoplasm.
Cynthia Dennis, Emilie Brasset, Arpita Sarkar, Chantal Vaury   +3 more
doaj   +1 more source

Understanding the Effects of Trenbolone Acetate, Polyamine Precursors, and Polyamines on Proliferation, Protein Synthesis Rates, and the Abundance of Genes Involved in Myoblast Growth, Polyamine Biosynthesis, and Protein Synthesis in Murine Myoblasts

Biology, 2023
Research suggests that androgens increase skeletal muscle growth by modulating polyamine biosynthesis. As such, the objective of this study was to investigate effects of anabolic hormones, polyamine precursors, and polyamines relative to proliferation ...
Laura A. Motsinger, Lillian L. Okamoto, Nikole E. Ineck, Brynne A. Udy, Christopher L. Erickson, Youssef Harraq, Caleb C. Reichhardt, Gordon K. Murdoch, Kara Jean Thornton   +8 more
doaj   +1 more source

Increasing cell density globally enhances the biogenesis of Piwi-interacting RNAs in Bombyx mori germ cells. [PDF]

, 2017
Piwi proteins and their bound Piwi-interacting RNAs (piRNAs) are predominantly expressed in the germline and play crucial roles in germline development by silencing transposons and other targets.
Honda, Shozo, Kawamura, Takuya, Kirino, Yohei, Kirino, Yoriko, Loher, Phillipe, Morichika, Keisuke, Rigoutsos, Isidore, Shigematsu, Megumi   +7 more
core   +2 more sources

Attachment of the RNA degradosome to the bacterial inner cytoplasmic membrane prevents wasteful degradation of rRNA in ribosome assembly intermediates.

PLoS Biology, 2023
RNA processing and degradation shape the transcriptome by generating stable molecules that are necessary for translation (rRNA and tRNA) and by facilitating the turnover of mRNA, which is necessary for the posttranscriptional control of gene expression ...
Lydia Hadjeras, Marie Bouvier, Isabelle Canal, Leonora Poljak, Quentin Morin-Ogier, Carine Froment, Odile Burlet-Schlitz, Lina Hamouche, Laurence Girbal, Muriel Cocaign-Bousquet, Agamemnon J Carpousis   +10 more
doaj   +1 more source

The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells. [PDF]

, 2017
Transfer RNAs (tRNAs) function in translational machinery and further serves as a source of short non-coding RNAs (ncRNAs). tRNA-derived ncRNAs show differential expression profiles and play roles in many biological processes beyond translation ...
Honda, Shozo, Kawamura, Takuya, Kirino, PhD, Yohei, Loher, Phillipe, Morichika, Keisuke, Rigoutsos, Isidore   +5 more
core   +2 more sources

Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting

Nature Communications, 2020
RNA polymerase I (Pol I) catalyses the transcription of ribosomal RNA precursors, and its transcription initiation mechanism differs from that of Pol II and Pol III.
Michael Pilsl, Christoph Engel
doaj   +1 more source