MicroRNA-122 dependent binding of Ago2 protein to hepatitis C virus RNA is associated with enhanced RNA stability and translation stimulation. [PDF]
Translation of Hepatitis C Virus (HCV) RNA is directed by an internal ribosome entry site (IRES) in the 5'-untranslated region (5'-UTR). HCV translation is stimulated by the liver-specific microRNA-122 (miR-122) that binds to two binding sites between ...
K Dominik Conrad +6 more
doaj +1 more source
Ribosomal Precursor RNA in Saccharomyces carlsbergensis [PDF]
Several lines of evidence for the occurrence of ribosomal precursor RNA in yeast are presented. This ribosomal precursor RNA has been found in the nuclear fraction, it is rapidly labeled with radioactive nucleotides and sediments faster than the two ribosomal RNAs.
J, Retèl, R J, Planta
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From Formamide to RNA, the Path Is Tenuous but Continuous
Reactions of formamide (NH2COH) in the presence of catalysts of both terrestrial and meteoritic origin yield, in plausible and variegated conditions, a large panel of precursors of (pre)genetic and (pre)metabolic interest. Formamide chemistry potentially
Samanta Pino +4 more
doaj +1 more source
The Drosophila ZAD zinc finger protein Kipferl guides Rhino to piRNA clusters
RNA interference systems depend on the synthesis of small RNA precursors whose sequences define the target spectrum of these silencing pathways. The Drosophila Heterochromatin Protein 1 (HP1) variant Rhino permits transcription of PIWI-interacting RNA ...
Lisa Baumgartner +5 more
doaj +1 more source
MicroRNA-like RNAs from the same miRNA precursors play a role in cassava chilling responses [PDF]
MicroRNAs (miRNAs) are known to play important roles in various cellular processes and stress responses. MiRNAs can be identified by analyzing reads from high-throughput deep sequencing.
Chen, Xin +5 more
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A new yeast poly(A) polymerase complex involved in RNA quality control [PDF]
Eukaryotic cells contain several unconventional poly(A) polymerases in addition to the canonical enzymes responsible for the synthesis of poly(A) tails of nuclear messenger RNA precursors.
Štěpánka Vaňáčová +71 more
core +4 more sources
Gene induction during differentiation of human monocytes into dendritic cells: an integrated study at the RNA and protein levels [PDF]
Changes in gene expression occurring during differentiation of human monocytes into dendritic cells were studied at the RNA and protein levels. These studies showed the induction of several gene classes corresponding to various biological functions ...
Angénieux, C. +9 more
core +3 more sources
Diversity of Endonuclease V: From DNA Repair to RNA Editing
Deamination of adenine occurs in DNA, RNA, and their precursors via a hydrolytic reaction and a nitrosative reaction. The generated deaminated products are potentially mutagenic because of their structural similarity to natural bases, which in turn leads
Isao Kuraoka
doaj +1 more source
Role of RNA Interference (RNAi) in the Moss Physcomitrella patens [PDF]
RNA interference (RNAi) is a mechanism that regulates genes by either transcriptional (TGS) or posttranscriptional gene silencing (PTGS), required for genome maintenance and proper development of an organism.
Arif, Muhammad Asif +2 more
core +3 more sources
Precursors to small molecular weight RNA components [PDF]
Metabolically long-lived RNA components such as tRNA and rRNA are formed from unstable larger precursors [ 1,2] . Baby Hamster Kidney cells (BHK-2 1 cells) contain four small mol. wt RNA components (sm RNA) with a metabolic half-life of 5-7 days [3] . The size of these components (D, C, A, and L) was determined to be from 145 to 235 nucleotides based ...
Frederiksen, Sune, Hellung-Larsen, Per
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