Results 41 to 50 of about 249,606 (193)
Methods to study splicing from high-throughput RNA Sequencing data [PDF]
Methods Mol Biol. 2014;1126:357-97, 2013 The development of novel high-throughput sequencing (HTS) methods for RNA (RNA-Seq) has provided a very powerful mean to study splicing under multiple conditions at unprecedented depth. However, the complexity of the information to be analyzed has turned this into a challenging task.
arxiv +1 more source
The role of alternative splicing in cancer [PDF]
Transcription, 2017 The functional capacity of cells is defined by the transcriptome. Many recent studies have identified variations in the transcriptome of tumors due to alternative splicing changes, as well as mutations in splicing factors and regulatory signals in most tumor types.
Babita Singh, Eduardo Eyras
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A study of alternative splicing in the pig [PDF]
BMC Research Notes, 2010 Since at least half of the genes in mammalian genomes are subjected to alternative splicing, alternative pre-mRNA splicing plays an important contribution to the complexity of the mammalian proteome. Expressed sequence tags (ESTs) provide evidence of a great number of possible alternative isoforms.
Hillig, Ann-Britt Nygaard +5 more
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Attacking Image Splicing Detection and Localization Algorithms Using Synthetic Traces [PDF]
arXiv, 2022 Recent advances in deep learning have enabled forensics researchers to develop a new class of image splicing detection and localization algorithms. These algorithms identify spliced content by detecting localized inconsistencies in forensic traces using Siamese neural networks, either explicitly during analysis or implicitly during training.
arxiv
An alternative definition of splicing
Theoretical Computer Science, 2006 AbstractIn this paper, we propose a new definition of the language generated by a splicing system, motivated by both biochemical and mathematical considerations. The main feature of the new definition is that by applying a splicing rule, we not only create new strings, but also allow for the removal of the strings entering the rule.
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Alternative Splicing in Apicomplexan Parasites [PDF]
mBio, 2019 Alternative splicing is a widespread, essential, and complex component of gene regulation. Apicomplexan parasites have long been recognized to produce alternatively spliced transcripts for some genes and can produce multiple protein products that are essential for parasite growth.
Lee M. Yeoh +3 more
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Mechano-Regulation of Alternative Splicing [PDF]
Current Genomics, 2013 Alternative splicing contributes to the complexity of proteome by producing multiple mRNAs from a single gene. Affymetrix exon arrays and experiments in vivo or in vitro demonstrated that alternative splicing was regulated by mechanical stress. Expression of mechano-growth factor (MGF) which is the splicing isoform of insulin-like growth factor 1(IGF-1)
Liling Tang, Huan Liu
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Alternative splicing: The lord of the rings
Nature Plants, 2017 Fil: Ariel, Federico Damian. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Centro Cientifico Tecnologico Conicet - Santa Fe. Instituto de Agrobiotecnologia del Litoral. Universidad Nacional del Litoral.
Ariel, Federico, Crespi, Martin
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Alternative Splicing in Lung Cancer [PDF]
Journal of Thoracic Oncology, 2009 Alterations in alternative splicing affect essential biologic processes and are the basis for a number of pathologic conditions, including cancer. In this review we will summarize the evidence supporting the relevance of alternative splicing in lung cancer. An example that illustrates this relevance is the altered balance between Bcl-xL and Bcl-xS, two
Luis M. Montuenga, Ruben Pio
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Editorial on alternative splicing and disease [PDF]
RNA Biology, 2010 (2010). Editorial on alternative splicing and disease. RNA Biology: Vol. 7, No. 4, pp. 388-389.
Barta Andrea, Schuemperli Daniel
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